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Drug-Target Interaction

Drug

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PubChem ID:439153
Structure:
Synonyms:
1,4-Dihydronicotinamide adenine dinucleotide
58-68-4
AC1L96RW
Adenosine 5'-(trihydrogen diphosphate), P'->5'-ester with 1,4-dihydro-1-beta-D-ribofuranosyl-3-pyridinecarboxamide (9CI)
Adenosine 5'-(trihydrogen pyrophosphate), 5'-5'-ester with 1,4-dihydro-1beta-D-ribofuranosylnicotinamide
Adenosine 5'-(trihydrogen pyrophosphate), 5'->5'-ester with 1,4-dihydro-1-beta-D-ribofuranosylnicotinamide (8CI)
adenosine 5'-{3-[1-(3-carbamoyl-1,4-dihydropyridin-1-yl)-1,4-anhydro-D-ribitol-5-yl] dihydrogen diphosphate}
Adenosine pyrophosphate, 5'->5'-ester with 1,4-dihydro-1-beta-D-ribofuranosylnicotinamide (7CI)
beta-DPNH
beta-NADH
bmse000054
C00004
CHEBI:16908
CHEMBL1234616
Codehydrase I, reduced
Codehydrogenase I, reduced
Coenzyme I, reduced
Cozymase I, reduced
DB00157
Dihydrocodehydrogenase I
Dihydrocozymase
dihydrodiphosphopyridine nucleotide
Dihydronicotinamide adenine dinucleotide
Dihydronicotinamide mononucleotide
Diphosphopyridine nucleotide
diphosphopyridine nucleotide reduced
DPN
DPN+
DPNH
NAD
NAD+
NAD-reduced
NADH
NADH+H+
NADH2
NAI
NAJ
NChemBio.2007.9-comp15
Nicotinamide adenine dinucleotide
nicotinamide adenine dinucleotide (reduced)
nicotinamide adenine dinucleotide reduced
Nicotinaminde-Adenine-Dinucleotide
Reduced codehydrogenase I
Reduced diphosphopyridine nucleotide
Reduced Nicotinamide Adenine Dinucleotide
Reduced nicotinamide adenine diphosphate
Reduced nicotinamide-adenine dinucleotide
[(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[[(
[(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[[(2R,3S,4R,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-phosphinic acid
[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[(2R,3S,4R,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate

Target

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Uniprot ID:SSDH_HUMAN
Synonyms:
Aldehyde dehydrogenase family 5 member A1
NAD(+)-dependent succinic semialdehyde dehydrogenase
Succinate-semialdehyde dehydrogenase, mitochondrial
EC-Numbers:1.2.1.24
Organism:Homo sapiens
Human
PDB IDs:2W8N 2W8O 2W8P 2W8Q 2W8R
Structure:
2W8R

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: