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Drug-Target Interaction

Drug

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PubChem ID:4236
Structure:
Synonyms:
(+)-modafinil
(+-)-Modafinil
(-)-2-((R)-(Diphenylmethyl)sulfinyl)acetamide
112111-43-0
112111-49-6
2-((Diphenylmethyl)sulfinyl)acetamide
2-(Benzhydrylsulfinyl)acetamide
2-benzhydrylsulfinylacetamide
2-[(Diphenylmethyl)sulfinyl]-?acetamide
2-[(diphenylmethyl)sulfinyl]acetamide
2-[di(phenyl)methylsulfinyl]acetamide
68693-11-8
AC-1382
AC1L1HPP
Acetamide, 2-((diphenylmethyl)sulfinyl)-
Acetamide, 2-((diphenylmethyl)sulfinyl)-, (-)-
Acetamide, 2-[(diphenylmethyl)sulfinyl]-
AFT-801
AKOS004118314
Alertec
Ambap1002
Armodafinil [INN]
Attenace
BIDD:GT0714
BRD-A16332958-001-02-4
BSPBio_002270
C15H15NO2S
CCG-39511
CEP 1538
CEP-10953
CEP-1538
CHEBI:417124
CHEMBL1373
CN-801
CPD000058957
CRL 40476
CRL-40476
D01832
DB00745
DEA No. 1680
HMS1922F12
HMS2051P17
HMS2093D15
HMS3264I03
HSDB 7585
I06-0190
L001269
LS-176682
M6940_SIGMA
MLS000759427
MODAFINIL
Modafinil (JAN/USAN/INN)
Modafinil [USAN:INN]
Modafinilo
Modafinilo [Spanish]
Modafinilum
Modafinilum [Latin]
Modasomil
Modavigil
Moderateafinil
Modiodal
NCGC00095176-01
NCGC00095176-02
NCGC00095176-03
NCGC00095176-04
NCGC00095176-05
NCGC00095176-06
Provigil
Provigil (TN)
Pulmicort
SAM001246587
SMR000058957
Sparlon
SPBio_001724
SPECTRUM1505361
Spectrum2_001712
ST50819508
TL8004816
UNII-R3UK8X3U3D
Vigil
ATC-Codes:
Side-Effects:
Side-EffectFrequency
agranulocytosis0.0010
psychosis0.0010
arthrosis0
pruritus0
psoriasis0
pyuria0
hyperacusis0
rhinitis0
sinusitis0
sweating0
syncope0
tachycardia0
tooth disorder0
tremor0
urinary tract infection0
polyuria0
pneumonia0
leg cramps0
leukocytosis0
lung disorder0
mediastinal disorders0
nausea0
nervousness0
pain0
palpitations0
pancytopenia0
paresthesia0
periodontal abscess0
personality disorder0
pharyngitis0
urticaria0
vertigo0
eye pain0
dry skin0
myalgia0
abdominal pain upper0
disturbance in attention0
elevated liver enzymes0
depressed mood0
photosensitivity0
bradycardia0
ecg abnormal0
urinary frequency0
insomnia0
hearing loss0
ventricular extrasystoles0
neck rigidity0
viral infection0
abnormal vision0
vomiting0
weight gain0
weight loss0
dry mouth0
urinary retention0
chills0
agitation0
emotional lability0
peripheral edema0
mouth ulceration0
migraine0
allergic reaction0
abdominal pain0
back pain0
bronchitis0
neck pain0
chest pain0
confusion0
conjunctivitis0
constipation0
cough0
cystitis0
decreased libido0
drug eruption0
contact dermatitis0
diarrhea0
ataxia0
asthma0
albuminuria0
amblyopia0
amnesia0
anaphylaxis0
anemia0
angioedema0
anorexia0
anxiety0
apnea0
arrhythmia0
arthralgia0
arthritis0
asthenia0
dizziness0
dysmenorrhea0
seasonal allergic rhinitis0
headache0
cardiac arrest0
heart disease0
hematuria0
herpes simplex0
hyperglycemia0
hypersensitivity0
hypertension0
hypotension0
hypothermia0
impotence0
infection0
hallucinations0
gingivitis0
dyspepsia0
dyspnea0
ear pain0
ecchymosis0
edema0
eosinophilia0
toxic epidermal necrolysis0
epistaxis0
erythema multiforme0
rash0
fever0
flatulence0
gastroenteritis0
influenza0

Target

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Uniprot ID:CP2C9_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC9
Cytochrome P450 2C9
P-450MP
P450 MP-4/MP-8
P450 PB-1
S-mephenytoin 4-hydroxylase
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:1OG2 1OG5 1R9O
Structure:
1R9O

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----

References: