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Drug-Target Interaction

Drug

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PubChem ID:42113
Structure:
Synonyms:
(+)-2-difluoromethyl 1,2,2,2-tetrafluoroethyl ether
(+-)-2-Difluoromethyl 1,2,2,2-tetrafluoroethyl ether
1,1,1,2-tetrafluoro-2-(difluoromethoxy)ethane
2-(difluoromethoxy)-1,1,1,2-tetrafluoroethane
57041-67-5
AC1L274J
AC1Q4ICY
C07519
C3H2F6O
CHEBI:4445
CHEMBL1200733
D00546
DB01189
Desflurane
Desflurane (JAN/USP/INN)
Desflurane (USP/INN)
Desflurane [USAN:INN]
Desflurano
Desflurano [INN-Spanish]
Desfluranum
Desfluranum [INN-Latin]
difluoromethyl 1,2,2,2-tetrafluoroethyl ether
Ethane, 2-(difluoromethoxy)-1,1,1,2-tetrafluoro-
ethane, 2-(difluoromethoxy)-1,1,1,2-tetrafluoro-, (+)-
Ethane, 2-(difluoromethoxy)-1,1,1,2-tetrafluoro-, (+-)-
I 653
I-653
I653
LS-65505
PC6781E
r-e 236ea1
Suprane
Suprane (TN)
UNII-CRS35BZ94Q
ATC-Codes:
Side-Effects:
Side-EffectFrequency
abnormal electrocardiogram0.0010
malignant hyperthermia0.0010
myocardial infarct0.0010
pruritus0.0010
hepatic failure0.0010
agitation0.0010
myocardial ischemia0.0010
hepatic necrosis0.0010
myalgia0.0010
hypoxia0.0010
bigeminy0.0010
hyperkalemia0.0010
hepatitis0.0010
dizziness0.0010
fever0.0010
dyspnea0.0010
asthma0.0010
arrhythmia0.0010
hemorrhage0.0010
conjunctivitis0
cough0
bradycardia0
bronchospasm0
vomiting0
tachycardia0
increased salivation0
pharyngitis0
nausea0
headache0
hypertension0
apnea0

Target

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Uniprot ID:GRIA1_HUMAN
Synonyms:
AMPA-selective glutamate receptor 1
GluR-1
GluR-A
GluR-K1
Glutamate receptor 1
Glutamate receptor ionotropic, AMPA 1
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: