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Drug-Target Interaction

Drug

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PubChem ID:4178
Structure:
Synonyms:
(+-)-1-(2,6-dimethylphenoxy)propan-2-amine
(2RS)-1-(2,6-dimethylphenoxy)-2-aminopropane
1-(2',6'-Dimethylphenoxy)-2-aminopropane
1-(2,6-Dimethylphenoxy)-2-propanamine
1-(2,6-dimethylphenoxy)propan-2-amine
1-methyl-2-(2,6-xylyloxy)ethanamine
1-Methyl-2-(2,6-xylyloxy)ethylamine
2-(2-Aminopropoxy)-1,3-DiMethyl-Benzene Hydrochloride
2-(2-aminopropoxy)-1,3-dimethylbenzene
2-Propanamine, 1-(2,6-dimethylphenoxy)-
31828-71-4
5370-01-4
5370-01-4 (hydrochloride)
AB00053683
AC1L1HL7
AC1Q2BC5
AC1Q2BC6
BPBio1_000026
BRD-A64092382-003-04-3
BRN 2092205
BSPBio_000022
BSPBio_002254
C07220
C11H17NO
CCG-204869
CHEBI:115958
CHEBI:6916
CHEMBL558
D08215
DB00379
DivK1c_000834
EINECS 250-825-7
ETHYLAMINE, 1-METHYL-2-(2,6-XYLYLOXY)-
I01-6374
IDI1_000834
KBio1_000834
KBio2_002082
KBio2_004650
KBio2_007218
KBio3_001474
KBioGR_001270
KBioSS_002082
KO-1173
KO1173
KOE-1173
Lopac0_000784
LS-68257
Mexiletene
Mexiletene hydrochloride
Mexiletina
Mexiletina [INN-Spanish]
Mexiletine
Mexiletine (INN)
Mexiletine HCL
Mexiletine [INN:BAN]
Mexiletinum
Mexiletinum [INN-Latin]
Mexilitine
Mexitil
Mexityl
NCGC00015659-02
NCGC00015659-03
NCGC00015659-04
NCGC00015659-05
NCGC00015659-06
NCGC00015659-07
NCGC00015659-08
NCGC00015659-09
NCGC00015659-10
NCGC00015659-11
NCGC00162253-01
NCGC00162253-02
NINDS_000834
Prestwick0_000241
Prestwick1_000241
Prestwick2_000241
Prestwick3_000241
SBB070242
SPBio_002241
Spectrum3_000727
Spectrum4_000795
Spectrum5_001279
Spectrum_001602
UNII-1U511HHV4Z
ATC-Codes:
Side-Effects:
Side-EffectFrequency
ataxia0.0010
pulmonary infiltration0.0010
pulmonary fibrosis0.0010
pancreatitis0.0010
nystagmus0.0010
hypersensitivity reaction0.0010
congestive heart failure0.0010
dyspepsia0.0010
drowsiness0.0010
psychosis0
palpitations0
heartburn0
pain0
upper gi bleeding0
decreased libido0
shock0
vomiting0
av block0
tinnitus0
diarrhea0
chest pain0
hepatitis0
exfoliative dermatitis0
dysphagia0
memory loss0
hepatic necrosis0
nausea0
malaise0
hypotension0
hot flashes0
increased sweating0
leukopenia0
hallucinations0
peptic ulcer0
arthralgia0
pharyngitis0
muscle cramps0
tremor0
loss of consciousness0
alopecia0
syncope0
headache0
myelofibrosis0
hiccup0
dry skin0
lightheadedness0
blurred vision0
positive ana0
fever0
liver function tests abnormal0
angina pectoris0
paresthesia0
numbness0
esophageal ulcer0
constipation0
agranulocytosis0
rash0
thrombocytopenia0
impotence0
nervousness0
fatigue0
weakness0
dry mouth0
dyspnea0
convulsions0
abdominal pain0
urinary hesitancy0
dizziness0
seizures0
edema0
bradycardia0
neutropenia0
stevens - johnson syndrome0
confusion0
hypertension0

Target

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Uniprot ID:Q6XP50_HUMAN
Synonyms:
Cytochrome P450
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: