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Drug-Target Interaction

Drug

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PubChem ID:4171
Structure:
Synonyms:
(RS)-Metoprolol
1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol
1-(Isopropylamino)-3-(p-(2-methoxyethyl)phenoxy)-2-propanol
1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol
1-[(1-methylethyl)amino]-3-({4-[2-(methyloxy)ethyl]phenyl}oxy)propan-2-ol
1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
2-Propanol, 1-(4-(2-methoxyethyl)phenoxy)-3-((1-methylethyl)amino)-
2-Propanol, 1-(4-(2-methoxyethyl)phenoxy)-3-((1-methylethyl)amino)-, (+-)-
2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-,
2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (.+/-.)-
3-[4-(2-methoxyethyl)phenoxy]-1-(propan-2-ylamino)propan-2-ol
37350-58-6
51384-51-1
54163-88-1
AB00053499
Beatrolol
Beloc-Duriles
Betaloc
Betaloc-Astra
Betalok
C07202
C15H25NO3
CCRIS 4198
CGP 2175
CGP-2175
CHEBI:6904
D02358
DB00264
dl-Metoprolol
EINECS 253-483-7
EINECS 257-166-4
H 93-26
HSDB 6531
Lopresor
LOPRESSIDONE
Lopressor
LS-122450
Metoprolol
Metoprolol (USAN/INN)
Metoprolol succinate
Metoprolol Tartrate
Metoprolol [USAN:BAN:INN]
Metoprolol [USAN:INN:BAN]
Metoprololum [INN-Latin]
NCGC00021148-02
NCGC00021148-03
NCGC00021148-04
Preblok
Presolol
Seloken
Spesicor
Spesikor
Toprol
TOPROL-XL
ATC-Codes:
Side-Effects:
Side-EffectFrequency
heart failure0.17368424
hypotension0.1565714
bradycardia0.07844
third degree heart block0.047
heart block0.04152173
dizziness0.0056923074
vertigo0.0056923074
shock0.0010
increased sweating0.00077
impotence0.00077
nervousness0.00077
hepatitis0.00077
anxiety0.00077
thrombocytopenia0.00077
arthralgia0.00077
paresthesia0.00077
photosensitivity0.00077
vomiting0.00077
hallucinations0.00077
urticaria0.00071
confusional state0.0006
myocardial infarction0.00018
syncope0.0
memory loss0.0
sore throat0.0
purpura0.0
ventricular tachycardia0.0
pneumonia0.0
agranulocytosis0.0
arrhythmia0.0
av block0.0
cerebrovascular disorder0.0
chest pain0.0
coronary artery disorder0.0
mental depression0.0
diabetes mellitus0.0
dyspnea0.0
fatigue0.0
fever0.0
abdominal pain0.0
sweating0
peripheral edema0
palpitations0
cold extremities0
muscle cramps0
tachycardia0
arterial insufficiency0
cardiac arrest0
congestive heart failure0
bronchospasm0
weakness0
constipation0
rash0
somnolence0
rhinitis0
amnesia0
emotional lability0
headache0
arthritis0
shortness of breath0
dry eyes0
heartburn0
claudication0
insomnia0
postural hypotension0
wheezing0
lightheadedness0
coma0
memory impairment0
weight gain0
hot flashes0
nausea0
decreased libido0
pain0
sexual dysfunction0
gangrene0
personality disorder0
retroperitoneal fibrosis0
dry mouth0
pruritus0
hypoglycemia0
psoriasis0
sinus arrest0
alopecia0
musculoskeletal pain0
flushing0
jaundice0
concentration impaired0
skin lesion0
tinnitus0
diarrhea0
nightmares0
edema0
hypersensitivity0
flatulence0
blurred vision0
conjunctivitis0
leukopenia0
dyspnea on exertion0

Target

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Uniprot ID:ADRB1_HUMAN
Synonyms:
Beta-1 adrenergic receptor
Beta-1 adrenoceptor
Beta-1 adrenoreceptor
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----
----
-55--
--190-
--320-

References: