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Drug-Target Interaction

Drug

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PubChem ID:4060
Structure:
Synonyms:
(+-)-5-Ethyl-3-methyl-5-phenylhydantoin
(+-)-Mephenytoin
(-)-5-Ethyl-3-methyl-5-phenylhydantoin
2, 4-Imidazolidinedione,
2, 4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-
2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-
2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-, (+-)-
3-Ethylnirvanol
3-Methyl-5, 5-ethylphenylhydantoin
3-Methyl-5,5-ethylphenylhydantoin
3-Methyl-5,5-phenylethylhydantoin
3-Methyl-5-ethyl-5-phenylhydantoin
5 Ethyl 3 Methyl 5 Phenylhydantoin
5-24-08-00093 (Beilstein Handbook Reference)
5-Ethyl-3-methyl-5-phenyl-2,4(3H,5H)-imidazoledione
5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione
5-Ethyl-3-methyl-5-phenylhydantoin
5-Ethyl-3-methyl-5-phenylimidazolidin-2,4-dione
5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione
5-Ethyl-5-fenyl-3-methylhydantoin
5-Ethyl-5-fenyl-3-methylhydantoin [Czech]
50-12-4
A1073/0050334
AB00052368
AC-15964
AC1L1HBP
AIDS-124490
AIDS124490
BIM-0051837.0001
BPBio1_001338
BRD-A83937277-001-03-0
BRN 0017282
BSPBio_001216
C12H14N2O2
CHEMBL861
component of Hydantal
D00375
D008617
DB00532
DivK1c_000937
EINECS 200-012-8
Epiazin
Epilan
Fenantoin
Gerot-epilan
HMS1571M18
HMS2089J22
HMS2098M18
HMS2230E21
HMS502O19
HSDB 3581
Hydantal
Hydantoin, 5-ethyl-3-methyl-5-phenyl-
Hydantoin, 5-ethyl-3-methyl-5-phenyl-, (-)-
IDI1_000937
Insulton
KBio1_000937
KBio2_001974
KBio2_004542
KBio2_007110
KBioGR_001508
KBioSS_001974
l-3-Methyl-5-ethyl-5-phenylhydantoin
l-Mephenytoin
LS-76188
LS-76189
Mefenetoin
Mefenitoina
Mefenitoina [INN-Spanish]
Mephenetoinum
MEPHENTOIN
Mephenytoin
Mephenytoin (USP/INN)
Mephenytoin [USAN:INN]
Mephenytoine
Mephenytoine [INN-French]
Mephenytoinum
Mephenytoinum [INN-Latin]
Mesantoin
Mesantoin (TN)
Mesdontoin
Mesontoin
Methoin
Methyl hydantoin
Methyl Phenetoin
Methylphenetoin
Metydan
Mixture Name
MLS002154157
MU2276000
NCGC00165924-01
NCGC00165924-02
NINDS_000937
NSC 34652
NSC-34652
NSC34652
Oprea1_289074
Phenantoin
Phenetoin, Methyl
Phenylethylmethylhydantoin
Prestwick0_001108
Prestwick1_001108
Prestwick2_001108
Prestwick3_001108
Sacerno
Sedantional
Sedantoin
Sedantoinal
SMR001233457
SPBio_003088
Spectrum4_001094
Spectrum_001494
Triantoin
WLN: T5MVNV EHJ C1 E2 ER
ATC-Codes:
Side-Effects:
Side-EffectFrequency
irritability0
seizures0
eosinophilia0
vomiting0
nystagmus0
insomnia0
dermatitis0
edema0
exfoliative dermatitis0
aplastic anemia0
pancytopenia0
pulmonary fibrosis0
leukopenia0
megaloblastic anemia0
somnolence0
fatigue0
leukocytosis0
tremor0
conjunctivitis0
alopecia0
nausea0
anemia0
urticaria0
agranulocytosis0
thrombocytopenia0
hypersensitivity0
toxic epidermal necrolysis0
diplopia0
photophobia0
jaundice0
erythema multiforme0
weight gain0
dysarthria0
hepatitis0
nervousness0
lymphoma0
hemolytic anemia0
ataxia0
dizziness0
lupus0
neutropenia0
nephrosis0
stevens - johnson syndrome0
confusion0
lymphadenopathy0

Target

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Uniprot ID:CP2CJ_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC17
CYPIIC19
Cytochrome P450 2C19
Mephenytoin 4-hydroxylase
P450-11A
P450-254C
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----
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References: