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Drug-Target Interaction

Drug

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PubChem ID:3962
Structure:
Synonyms:
8-[2-(4-hydroxy-6-oxotetrahydro-2h-pyran-2-yl)ethyl]-3,7-dimethyl-1,2,3,7,
Butanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester, [1S-[1.alpha.(R*),3.alpha.,7.beta.,8.beta.(2S*,4S*),8a.beta.]]-
Lovastatin
NCGC00095278-01
NCGC00095278-02
Side-Effects:
Side-EffectFrequency
flatulence0.03844681
constipation0.02666667
headache0.02510639
diarrhea0.022083335
myalgia0.021239998
abdominal pain0.02055555
nausea0.02025
dyspepsia0.012000002
asthenia0.011315788
rash0.010326085
blurred vision0.010114287
muscle cramps0.00782
dizziness0.0069230758
vertigo0.0010
regurgitation0.0010
pancreatitis0.0010
ophthalmoplegia0.0010
nerve palsy0.0010
hypercholesterolemia0.0010
myopathy0.0010
chronic active hepatitis0.0010
insomnia0.0010
paresis0.0010
hepatic necrosis0.0010
tremor0.0010
dry mouth0.0010
cataracts0.0010
memory loss0.0010
shoulder pain0.0010
rhabdomyolysis0.0010
purpura0.0010
pruritus0.0010
cirrhosis0.0010
leg pain0.0010
loss of libido0.0010
chest pain0.0010
coronary atherosclerosis0.0010
gynecomastia0.0010
hepatoma0.0010
arthralgia0.00057
hypersensitivity0.00057
dermatomyositis0.00055
chills0.00045
vomiting0.00045
arthritis0.00045
thrombocytopenia0.00045
malaise0.00045
anxiety0.00045
anorexia0.00045
angioedema0.00045
hemolytic anemia0.00045
photosensitivity0.00045
anaphylaxis0.00045
positive ana0.00045
alopecia0.00045
vasculitis0.00045
leukopenia0.00045
jaundice0.00045
lupus0.00045
hepatitis0.00045
flushing0.00045
fever0.00045
paresthesia0.00045
peripheral neuropathy0.00045
polymyalgia rheumatica0.00045
urticaria0.00045
stevens - johnson syndrome0.00045
dyspnea0.00045
eosinophilia0.00045
toxic epidermal necrolysis0.00045
erythema multiforme0.00045
pain0
cancer0
influenza0
alkaline phosphatase increased0
urinary tract infection0
sinusitis0
back pain0
infection0

Target

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Uniprot ID:CP3A3_HUMAN
Synonyms:
EC-Numbers:-
Organism:-
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: