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Drug-Target Interaction

Drug

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PubChem ID:39468
Structure:
Synonyms:
(-)-Bunolol
(S)-5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-1(2H)-naphthalenone
1(2H)-Naphthalenone,
1(2H)-Naphthalenone, 5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-, (S)-
47141-42-4
5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydro-2H-naphthalen-1-one
5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydronaphthalen-1(2H)-one
Akbeta
Betagan
BPBio1_000917
BSPBio_000833
C07914
C17H25NO3
CAS-27912-14-7
CAS-47141-41-3
CCRIS 4375
CHEBI:6438
DB01210
Levobunolol
Levobunolol HCl
Levobunolol [INN:BAN]
Levobunololum [INN-Latin]
LS-175034
NCGC00016801-01
NCGC00016801-02
NCGC00016801-03
Prestwick0_000847
Prestwick1_000847
Prestwick2_000847
Prestwick3_000847
SPBio_002754
W-6412A
W-7000A
ATC-Codes:
Side-Effects:
Side-EffectFrequency
alopecia0
hypotension0
impotence0
iridocyclitis0
keratitis0
myasthenia gravis0
nasal congestion0
nausea0
palpitations0
paresthesia0
ptosis0
pruritus0
stevens - johnson syndrome0
cerebrovascular accident0
syncope0
urticaria0
bradycardia0
cerebral ischemia0
hypoglycemia0
hypersensitivity0
arrhythmia0
asthenia0
ataxia0
blepharoconjunctivitis0
blepharoptosis0
bronchospasm0
chest pain0
confusion0
diarrhea0
diplopia0
dizziness0
dyspnea0
rash0
headache0
cardiac arrest0
heart block0
congestive heart failure0
respiratory failure0

Target

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Uniprot ID:ADRB1_HUMAN
Synonyms:
Beta-1 adrenergic receptor
Beta-1 adrenoceptor
Beta-1 adrenoreceptor
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: