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Drug-Target Interaction

Drug

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PubChem ID:394493
Structure:
Synonyms:
()-oxazepam hemisuccinate sodium salt
AC1L98DY
Alimta
CHEBI:195145
CHEMBL59843
CID394493
L-Glutamic acid,
L-Glutamic acid, N-[4-[2-[2-amino-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl]ethyl]benzoyl]-
LY-231514
NCI60_035021
NSC698037
Pemetrexed

Target

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Uniprot ID:DYR_HUMAN
Synonyms:
Dihydrofolate reductase
EC-Numbers:1.5.1.3
Organism:Homo sapiens
Human
PDB IDs:1BOZ 1DHF 1DLR 1DLS 1DRF 1HFP 1HFQ 1HFR 1KMS 1KMV 1MVS 1MVT 1OHJ 1OHK 1PD8 1PD9 1PDB 1S3U 1S3V 1S3W 1U71 1U72 1YHO 2C2S 2C2T 2DHF 3EIG 3F8Y 3F8Z 3F91 3FS6 3GHC 3GHV 3GHW
Structure:
3GHW

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
7---
--1400-
--2300-
--6600-
--66000.0-

References: