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Drug-Target Interaction

Drug

show drug details
PubChem ID:3825
Structure:
Synonyms:
(+)-3-benzoyl-alpha-methylbenzeneacetic acid
(+-)-3-Benzoyl-alpha-methylbenzeneacetic acid
(+-)-m-Benzoylhydratropic acid
154907-35-4
172964-50-0
19,583 RP
19583 RP
2-(3-benzoylphenyl)propanoic acid
2-(3-Benzoylphenyl)propionic acid
2-(m-Benzoylphenyl)propionic acid
2-[3-(benzoyl)phenyl]propanoic acid
2-[3-(phenylcarbonyl)phenyl]propanoic acid
2-[3-Benzoylphenyl]propionic acid
22071-15-4
22161-86-0
3-BENZOYL-ALPHA-METHYLBENZENEACETIC ACID
3-Benzoylhydratropic acid
34016_FLUKA
34016_RIEDEL
AB00052249
AC-1486
AC1L1GST
AC1Q1LGA
Acide (benzoyl-3-phenyl)-2-propionique
Acide (benzoyl-3-phenyl)-2-propionique [French]
ACTRON
Alrheumat
Alrheumum
Alrheumun
Aneol
Benzeneacetic acid, 3-benzoyl-.alpha.-methyl-
Benzeneacetic acid, 3-benzoyl-alpha-methyl-
Benzeneacetic acid, 3-benzoyl-alpha-methyl-, (+-)-
Benzoylhydratropic Acid
BIDD:GT0443
BIM-0050664.0001
Bio-0742
BPBio1_000261
BRD-A97739905-001-05-9
BSPBio_000237
BSPBio_003037
C01716
C16H14O3
Capisten
CCG-39685
CCRIS 4508
CHEBI:6128
CHEMBL571
CPD000040181
D00132
DB01009
Dexal
DivK1c_000598
DKYWVDODHFEZIM-UHFFFAOYSA-
EINECS 244-759-8
Epatec
EU-0100686
Fastum
FT-0082352
HMS1568L19
HMS1921B12
HMS2089B16
HMS2092L19
HMS2095L19
HMS2234H16
HMS3259I05
HMS3262I13
HMS501N20
hydratropic acid, m-benzoyl-, (+)-
Hydratropic acid, m-benzoyl-, (+-)-
I01-3439
IDI1_000598
Iso-K
K 1751
K0038
K1751_SIAL
K1751_SIGMA
K2012_SIAL
KBio1_000598
KBio2_001789
KBio2_004357
KBio2_006925
KBio3_002537
KBioGR_000435
KBioSS_001789
Kefenid
Ketoprofen
ketoprofen (+)
Ketoprofen (+-)
Ketoprofen (JP15/USP/INN)
Ketoprofen (JP16/USP/INN)
Ketoprofen [USAN:BAN:INN:JAN]
Ketoprofen [USAN:INN:BAN:JAN]
Ketoprofen-Supplied by Selleck Chemicals
Ketoprofene
Ketoprofene [INN-French]
Ketoprofeno
Ketoprofeno [INN-Spanish]
Ketoprofenum
Ketoprofenum [INN-Latin]
Ketopron
Ketoprophene
L'Acide (benzoyl-3-phenyl)-2-propionique
Lertus
Lopac0_000686
LS-28621
LS-7470
m-Benzoylhydratropic acid
Menamin
Meprofen
MLS000028446
MLS000079024
MLS001201752
MLS001306444
NCGC00015578-02
NCGC00015578-03
NCGC00015578-04
NCGC00015578-05
NCGC00015578-07
NCGC00015578-08
NCGC00094043-01
NCGC00094043-02
NCGC00094043-03
NCGC00094043-04
NINDS_000598
Oprea1_117113
Orudis
Orudis (TN)
ORUDIS KT
Orudis, Oruvail, Ketoflam, Orudis KT, Ketoprofen
Orugesic
Oruvail
Oscorel
Prestwick0_000219
Prestwick1_000219
Prestwick2_000219
Prestwick3_000219
Prestwick_617
Profenid
Propionic acid, 2-(3-benzoylphenyl)-
racemic-Ketoprofen
RP 19583
RP-19583
RU 4733
S1645_Selleck
SAM002264620
SMR000040181
SPBio_000952
SPBio_002158
SPECTRUM1501215
Spectrum2_000956
Spectrum3_001479
Spectrum4_000028
Spectrum5_001254
Spectrum_001309
STOCK2S-03814
Toprec
Toprek
UNII-90Y4QC304K
UNM-0000306100
ATC-Codes:
Side-Effects:
Side-EffectFrequency
interstitial nephritis0.0010
renal failure0.0010
retinal hemorrhage0.0010
rhinitis0.0010
septicemia0.0010
shock0.0010
salivation0.0010
stevens - johnson syndrome0.0010
stomatitis0.0010
sweating0.0010
purpura0.0010
pruritus0.0010
pharyngitis0.0010
nephrotic syndrome0.0010
nervousness0.0010
nightmares0.0010
pain0.0010
palpitation0.0010
pancreatitis0.0010
paresthesia0.0010
peptic ulcer0.0010
personality disorder0.0010
tachycardia0.0010
thrombocytopenia0.0010
intestinal ulceration0.0010
malaise0.0010
myalgia0.0010
menometrorrhagia0.0010
fecal occult blood0.0010
rectal hemorrhage0.0010
photosensitivity0.0010
insomnia0.0010
hearing impairment0.0010
eye pain0.0010
migraine0.0010
onycholysis0.0010
tinnitus0.0010
urticaria0.0010
vertigo0.0010
vomiting0.0010
weight gain0.0010
weight loss0.0010
dry mouth0.0010
peripheral vascular disease0.0010
chills0.0010
allergic reaction0.0010
nausea0.0010
abdominal pain0.0010
exfoliative dermatitis0.0010
diabetes mellitus0.0010
diarrhea0.0010
dizziness0.0010
somnolence0.0010
dyspepsia0.0010
dyspnea0.0010
eczema0.0010
edema0.0010
constipation0.0010
conjunctivitis0.0010
confusion0.0010
agranulocytosis0.0010
alopecia0.0010
amnesia0.0010
anaphylaxis0.0010
anemia0.0010
anorexia0.0010
arrhythmias0.0010
bronchospasm0.0010
ulcerative colitis0.0010
toxic epidermal necrolysis0.0010
epistaxis0.0010
hemoptysis0.0010
hepatitis0.0010
hypertension0.0010
hyponatremia0.0010
impotence0.0010
infection0.0010
jaundice0.0010
melena0.0010
aseptic meningitis0.0010
hematuria0.0010
hematemesis0.0010
congestive heart failure0.0010
eructation0.0010
erythema multiforme0.0010
rash0.0010
flatulence0.0010
gastritis0.0010
gynecomastia0.0010
hallucination0.0010
headache0.0010
myocardial infarction0.0010
dysphoria0
gastrointestinal hemorrhage0

Target

show target details
Uniprot ID:AK1C3_HUMAN
Synonyms:
17-beta-HSD 5
17-beta-hydroxysteroid dehydrogenase type 5
3-alpha-HSD type 2
3-alpha-HSD type II, brain
3-alpha-hydroxysteroid dehydrogenase type 2
Aldo-keto reductase family 1 member C3
Chlordecone reductase homolog HAKRb
DD-3
DD3
Dihydrodiol dehydrogenase 3
Dihydrodiol dehydrogenase type I
HA1753
Indanol dehydrogenase
PGFS
Prostaglandin F synthase
Testosterone 17-beta-dehydrogenase 5
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
EC-Numbers:1.-.-.-
1.1.1.112
1.1.1.188
1.1.1.213
1.1.1.63
1.1.1.64
1.3.1.20
Organism:Homo sapiens
Human
PDB IDs:1RY0 1RY8 1S1P 1S1R 1S2A 1S2C 1XF0 1ZQ5 2F38 2FGB
Structure:
2FGB

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--33000-

References: