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Drug-Target Interaction

Drug

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PubChem ID:3823
Structure:
Synonyms:
1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine
79156-75-5
CHEBI:48339
Fungarest
Fungoral
Ketoconazol
Ketoconazole
Ketoderm
KW 1414
NCI60_002728
NSC317629
Oprea1_683648
piperazine,
Side-Effects:
Side-EffectFrequency
abdominal pain0
nausea0
pain0
papilledema0
paresthesia0
pruritus0
swelling0
thrombocytopenia0
erythema0
urticaria0
vomiting0
chills0
photophobia0
pyogenic granuloma0
dry skin0
scalp seborrhea0
eye swelling0
acne0
leukopenia0
keratoconjunctivitis sicca0
alopecia0
anaphylaxis0
hemolytic anemia0
arrhythmia0
dermatitis0
contact dermatitis0
diarrhea0
dizziness0
somnolence0
rash0
fever0
gynecomastia0
headache0
hypersensitivity0
hypertriglyceridemia0
impetigo0
impotence0
allergic reaction0

Target

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Uniprot ID:CP51_YEAST
Synonyms:
CYPLI
Cytochrome P450 51
Lanosterol 14-alpha demethylase
P450-14DM
P450-LIA1
Sterol 14-alpha demethylase
EC-Numbers:1.14.13.70
Organism:Baker's yeast
Saccharomyces cerevisiae
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: