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Drug-Target Interaction

Drug

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PubChem ID:3758
Structure:
Synonyms:
1 Methyl 3 isobutylxanthine
1-methyl-3-(2-methylpropyl)-1,3,7-trihydropurine-2,6-dione
1-methyl-3-(2-methylpropyl)-3,7-dihydro-1H-purine-2,6-dione
1-methyl-3-(2-methylpropyl)-3,9-dihydro-1H-purine-2,6-dione
1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione
1-methyl-3-(propan-2-yl)-3,7-dihydro-1H-purine-2,6-dione
1-methyl-3-(propan-2-yl)-3,9-dihydro-1H-purine-2,6-dione
1-METHYL-3-ISOBUTYLXANTHINE
1H-Purine-2,6-dione, 3,7-dihydro-1-methyl-3-(2-methylpropyl)-
1H-Purine-2,6-dione, 3,7-dihydro-1-methyl-3-(2-methylpropyl)-;
1zkl
1zkn
28822-58-4
2hd1
2r8q
3 Isobutyl 1 methylxanthine
3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione
3,7-Dihydro-3-isobutyl-1-methyl-1H-purine-2,6-dione
3-ISOBUTHYL-1-METHYLXANTHINE
3-Isobutyl 1-methylxanthine
3-Isobutyl-1-methyl-2,6(1H,3H)-purinedione
3-isobutyl-1-methyl-3,7-dihydro-1H-purine-2,6-dione
3-isobutyl-1-methyl-3,9-dihydro-1H-purine-2,6-dione
3-isobutyl-1-methyl-7H-xanthine
3-isobutyl-1-methyl-9H-xanthine
3-Isobutyl-1-methylxanthine
3-Isobutyl-1-methyxanthine
3ecn
AC1L1GNB
AC1Q1PM4
AIDS-008701
AIDS008701
AKOS003390599
BCBcMAP01_000110
Bio-0605
Bio1_000456
Bio1_000945
Bio1_001434
Bio2_000407
Bio2_000887
BRD-K94979336-001-06-9
BSPBio_001153
BSPBio_003558
C10H14N4O2
C13708
CCG-39513
CCG-39624
CCRIS 4290
CHEBI:34795
CHEBI:43253
CHEMBL275084
cMAP_000087
CPD-5461
D015056
DB07954
DivK1c_000922
EINECS 249-259-3
EU-0100642
HMS1362I15
HMS1792I15
HMS1990I15
HMS2090J10
HMS2231C11
HMS3262A05
HMS502O04
HSCI1_000261
I 5879
I5879_SIGMA
I7018_SIGMA
IBM
IBMX
IDI1_000922
IDI1_002162
IN1293
Isobutylmethylxanthine
Isobutyltheophylline
KBio1_000922
KBio2_000493
KBio2_002566
KBio2_003061
KBio2_005134
KBio2_005629
KBio2_007702
KBio3_000905
KBio3_000906
KBio3_002878
KBio3_003044
KBioGR_000493
KBioGR_001344
KBioGR_002566
KBioSS_000493
KBioSS_002575
L001156
Lopac-I-5879
Lopac0_000642
LS-162537
Methyl-isobutylxanthine
methylisobutylxanthine
MLS001056732
MLS001066424
MolMap_000030
MolPort-001-737-339
MolPort-001-792-510
NCGC00015559-01
NCGC00015559-02
NCGC00015559-03
NCGC00015559-04
NCGC00015559-05
NCGC00015559-06
NCGC00015559-07
NCGC00015559-08
NCGC00015559-09
NCGC00015559-10
NCGC00015559-11
NCGC00094009-01
NCGC00094009-02
NCGC00094009-03
NCGC00094009-04
NCGC00094009-05
NCGC00094009-06
NINDS_000922
NSC 165960
NSC165960
Oprea1_135287
Oprea1_228781
PDSP1_000324
PDSP2_000322
SMR000326697
SPBio_001690
SPBio_001810
SPECTRUM1505298
SPECTRUM2300204
Spectrum2_001705
Spectrum2_001735
Spectrum3_001958
Spectrum4_001052
Spectrum5_001856
ST055758
STOCK1N-14620
STOCK1N-23901
WLN: T56 BM DN FNVNVJ F1Y1&1 H1
Xanthine, 3-isobutyl-1-methyl-
ZINC03861807
[Eur J Pharmacol 170: 35 (1989)]

Target

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Uniprot ID:PDE2A_HUMAN
Synonyms:
cGMP-dependent 3',5'-cyclic phosphodiesterase
CGS-PDE
cGSPDE
Cyclic GMP-stimulated phosphodiesterase
EC-Numbers:3.1.4.17
Organism:Homo sapiens
Human
PDB IDs:1Z1L
Structure:
1Z1L

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--12000-

References: