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Drug-Target Interaction

Drug

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PubChem ID:37015
Structure:
Synonyms:
1H-Pyrazolo(3,4-b)pyridine-5-carboxylic acid, 4-(butylamino)-1-ethyl-,
1H-Pyrazolo(3,4-b)pyridine-5-carboxylic acid, 4-(butylamino)-1-ethyl-, ethyl ester
1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid, 4-(butylamino)-1-ethyl-, ethyl ester
34966-41-1
4-Butylamino-1-ethyl-lH-pyrazolo-(3,4-b)pyridine-5-carboxylic acid ethyl ester
CARTAZOLATE
Cartazolate (USAN/INN)
Cartazolate [USAN:INN]
Cartazolato
Cartazolato [INN-Spanish]
Cartazolatum
Cartazolatum [INN-Latin]
D03413
Ethyl 4-(butylamino)-1-ethyl-1H-pyrazolo(3,4-b)-pyridine-5-carboxylate
Ethyl 4-(butylamino)-1-ethyl-1H-pyrazolo[3,4-b]-pyridine-5-carboxylate
NSC 166873
NSC166873
PDSP1_000995
PDSP2_000979
SQ 65396
SQ-65396

Target

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Uniprot ID:PDE5A_HUMAN
Synonyms:
CGB-PDE
cGMP-binding cGMP-specific phosphodiesterase
cGMP-specific 3',5'-cyclic phosphodiesterase
EC-Numbers:3.1.4.35
Organism:Homo sapiens
Human
PDB IDs:1RKP 1T9R 1T9S 1TBF 1UDT 1UDU 1UHO 1XOZ 1XP0 2CHM 2H40 2H42 2H44 3B2R 3BJC 3HC8 3HDZ
Structure:
3HDZ

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--180-

References: