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Drug-Target Interaction

Drug

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PubChem ID:3661
Structure:
Synonyms:
(+,-)-Tropyl tropate
(+/-)-Hyoscyamine
(,-)-tropyl tropate
(-)-Hyoscyamine
1-alpha-h,5-alpha-h-tropan-3-alpha-ol (+)-tropate (ester) (8ci)
1-alpha-H,5-alpha-H-Tropan-3-alpha-ol (+-)-tropate (ester) (8CI)
1.alpha.H,5.alpha.H-Tropan-3.alpha.-ol (.+/-.)-tropate (ester)
1alphah,5alphah-tropan-3alpha-ol (+)-tropate (ester)
1alphaH,5alphaH-Tropan-3alpha-ol (+-)-tropate (ester)
2-Phenylhydracrylic acid 3-alpha-tropanyl ester
51-55-8
78597-12-3
AB00514677
AI3-60219
alpha-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester
Atropin
Atropin [German]
Atropin-flexiolen
Atropina [Italian]
ATROPINE
Atropine [BAN]
Atropinol
Benzeneacetic acid, .alpha.-(hydroxymethyl)-
Benzeneacetic acid, .alpha.-(hydroxymethyl)- 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester endo-(.+/-.)-
Benzeneacetic acid, .alpha.-(hydroxymethyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, [3(S)-endo]-
Benzeneacetic acid, alpha-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester
benzeneacetic acid, alpha-(hydroxymethyl)-, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, endo-(+)-
Benzeneacetic acid, alpha-(hydroxymethyl)-, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, endo-(+-)-
benzeneacetic acid, alpha-(hydroxymethyl)-8-methyl-8-azabicyclo(3,2,1)oct-3-yl ester, endo-(+)-
Benzeneacetic acid, alpha-(hydroxymethyl)-8-methyl-8-azabicyclo(3,2,1)oct-3-yl ester, endo-(+-)-
beta-Phenyl-gamma-oxypropionsaeure-tropyl-ester [German]
beta-Phenyl-gamma-oxypropionsaure-tropyl-ester [German]
BPBio1_000386
BSPBio_000350
BSPBio_001874
CCRIS 3080
Daturine
DivK1c_000558
dl-Hyoscyamine
DL-Tropanyl 2-hydroxy-1-phenylpropionate
dl-Tropyltropate
EINECS 200-104-8
EU-0100567
Eyesules
HSDB 2199
Hyoscyamine
Hyoscyamine Hydrobromide
IDI1_000558
Isopto-atropine
KBio1_000558
KBio2_001639
KBio2_004207
KBio2_006775
KBio3_001374
KBioGR_002450
KBioSS_001639
L-Hyoscyamine
L-Hyoscyamine hydrobromide
Lopac0_000042
Lopac0_000567
NCGC00093951-01
NCGC00093951-02
NCGC00093951-03
NCGC00093951-04
NCGC00094699-01
NCGC00094699-02
NCGC00161600-01
NCGC00161600-02
NCGC00161600-03
NINDS_000558
Oprea1_442738
Prestwick0_000565
Prestwick1_000565
Prestwick2_000565
Prestwick3_000565
SDCCGMLS-0066623.P001
SMP1_000031
SPBio_000048
SPBio_002569
Spectrum2_000094
Spectrum3_000307
Spectrum4_001813
Spectrum5_000545
Spectrum_001159
Tropic acid, 3-alpha-tropanyl ester
Tropic acid, ester with tropine
Tropine tropate
Tropine, tropate (ester)
Troyl tropate
UPCMLD-DP018
UPCMLD-DP018:001
ATC-Codes:
Side-Effects:
Side-EffectFrequency
paranoia0
sweating0
swelling0
syncope0
junctional tachycardia0
sinus tachycardia0
supraventricular tachycardia0
tremor0
ventricular fibrillation0
stridor0
strabismus0
palpitations0
paralytic ileus0
weakness0
petechiae0
supraventricular extrasystoles0
pulmonary edema0
shock0
increased salivation0
ventricular tachycardia0
vertigo0
dry eyes0
blurred vision0
blindness0
elevated blood pressure0
paralysis0
manic0
insomnia0
respiratory failure0
excitement0
heat intolerance0
vomiting0
urinary retention0
polydipsia0
stupor0
agitation0
photophobia0
ventricular extrasystoles0
dry skin0
pain0
nausea0
confusion0
conjunctivitis0
constipation0
decreased libido0
dysphagia0
dehydration0
delirium0
dermatitis0
coma0
chest pain0
abdominal pain0
amnesia0
anaphylaxis0
anxiety0
arrhythmia0
ataxia0
atrial fibrillation0
blepharitis0
dizziness0
somnolence0
hypoglycemia0
hypokalemia0
hyponatremia0
irritability0
keratoconjunctivitis sicca0
laryngitis0
leukocytosis0
myocardial infarction0
hypersensitivity0
hyperglycemia0
dysarthria0
dyskinesia0
rash0
fatigue0
narrow angle glaucoma0
hallucinations0
headache0
cardiac arrest0
abdominal distention0

Target

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Uniprot ID:ACM1_HUMAN
Synonyms:
Muscarinic acetylcholine receptor M1
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
-0.9--
0.25---
0.32---
0.329---
0.683---
0.85---
0.89---
1---
1.6---
2---
2.4---

References: