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Drug-Target Interaction

Drug

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PubChem ID:36431
Structure:
Synonyms:
1,1-Cyclopentanediacetimide,
1,1-Cyclopentanediacetimide, N-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-, hydrochloride
33386-08-2
8-(4-(4-(2-Pyrimidinyl)-1-piperazinyl)butyl)-8-azaspiro(4.5)decane-7,9-dione hydrochloride
8-(4-(4-(2-Pyrimidinyl)-1-piperazinyl)butyl)-8-azaspiro(4.5)decane-7,9-dione monohydrochloride
8-Azaspiro(4,5)decane-7,9-dione, 8-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-, monohydrochloride
8-Azaspiro(4,5)decane-7,9-dione,8-(4-(4-(2-pyrimidinyl)piperizinyl)butyl)
8-Azaspiro(4.5)decane-7,9-dione, 8-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-,monohydrochloride
Ansitec
Anxinil
Anxiolan
APC-6002
APC-6003
Apo-Buspirone
B7148_SIGMA
Barpil
Bespar
Biron
Busirone
Buspar
Buspar (TN)
Buspimen
Buspinol
BUSPIRONE HCL
Buspirone hydrochloride
Buspirone hydrochloride (USP)
Buspirone hydrochloride [USAN]
C21H31N5O2.HCl
Censpar
CHEBI:3224
D00702
Effiplen
EINECS 251-489-4
Establix
EU-0100223
Itagil
Kallmiren
LS-22724
Lucelan
Mabuson
MJ 9022-1
MJ-9022-1
MLS000069796
MLS001076085
N-(4-(4-(2-Pyrimidinyl)-1-piperazinyl)butyl)-1,1-cyclopentanediacetamide monohydrochloride
N-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride
Narol
NCGC00093692-01
NCGC00093692-02
Nerbet
Normaton
Prestwick_711
Relac
Sburol
SMR000058186
Spamilan
Travin
Tutran
Side-Effects:
Side-EffectFrequency
insomnia1.0
weakness1.0
numbness1.0
nightmares1.0
nervousness1.0
nausea1.0
nasal congestion1.0
tremor1.0
headache1.0
paresthesia1.0
sweating1.0
blurred vision1.0
sore throat1.0
muscle aches1.0
lightheadedness1.0
dry mouth1.0
vomiting1.0
tinnitus1.0
tachycardia1.0
fatigue1.0
chest pain1.0
diarrhea1.0
skin rash1.0
confusion1.0
drowsiness1.0
constipation1.0
dizziness0.667
chills0.01
breakthrough bleeding0.01
irritable colon0.01
easy bruising0.01
muscle cramps0.01
anorexia0.01
menstrual irregularity0.01
dry skin0.01
spasms0.01
malaise0.01
hypotension0.01
hypersalivation0.01
arthralgia0.01
urinary frequency0.01
hair loss0.01
weight gain0.01
fever0.01
flatulence0.01
flushing0.01
rectal bleeding0.01
blisters0.01
shortness of breath0.01
weight loss0.01
hypertension0.01
pruritus0.009999999
edema0.009999999
seizures0.0082
syncope0.0082
hallucinations0.0082
photophobia0.0010
restlessness0.0010
vertigo0.0010
urinary retention0.0010
alcohol abuse0.0010
acne0.0010
bradycardia0.0010
amenorrhea0.0010
parkinsonism0.0010
angioedema0.0010
galactorrhea0.0010
allergic reactions0.0010
stiff neck0.0010
cardiomyopathy0.0010
urticaria0.0010
myocardial infarction0.0010
serotonin syndrome0.0010
flu0.0010
impotence0.0010
hiccups0.0010
congestive heart failure0.0010
dyskinesias0.0010
epistaxis0.0010
eosinophilia0.0010
enuresis0.0010
nocturia0.0010
cold intolerance0.0010
thrombocytopenia0.0010
ecchymosis0.0010
restless leg syndrome0.0010
cerebrovascular accident0.0010
ataxias0.0010
psychosis0.0010
leukopenia0.0010
erythema0.0010
hemorrhage0
muscle weakness0
aphonia0
dysuria0
euphoria0
anger0
stupor0
pelvic inflammatory disease0
eye pain0
palpitations0
conjunctivitis0
depersonalization0
emotional lability0
dysphoria0
excitement0
thinking abnormal0
feeling high0
urinary hesitancy0

Target

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Uniprot ID:CP3A3_HUMAN
Synonyms:
EC-Numbers:-
Organism:-
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: