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Drug-Target Interaction

Drug

show drug details
PubChem ID:35370
Structure:
Synonyms:
"3′-azido-3′-deoxythymidine"
1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)-5-methylpyrimidine-2,4-(1H,3H
1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)-5-methylpyrimidine-2,4-(1H,3H)-dione
1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione
3′-Azido-3′-deoxythymidine
3'- Azido-3'-deoxythymidine & Granulocyte-macrophage colony-stimulating factor
3'-Azido-2',3'-Dideoxythymidine
3'-Azido-2',3'-dideoxythymidine & sCD4(soluble recombinant protein)
3'-Azido-3'-deoxythymidine
3'-Azido-3'-deoxythymidine & CD4-Pseudomonas exotoxin A hybrid
3'-Azido-3'-deoxythymidine & Concanavalin A
3'-Azido-3'-deoxythymidine & Erythropoietin
3'-Azido-3'-deoxythymidine & Heteropolyoxotungstate PM-19
3'-Azido-3'-deoxythymidine & Interleukin-1
3'-Azido-3'-deoxythymidine & Interleukin-2
3'-Azido-3'-deoxythymidine & Interleukin-6
3'-Azido-3'-deoxythymidine & Lithium & Erythropoietin
3'-Azido-3'-deoxythymidine & Lithium & Granulocyte-macrophage colony-stimulating factor
3'-Azido-3'-deoxythymidine & Lithium & Interleukin-1
3'-Azido-3'-deoxythymidine & Lithium & Interleukin-6
3'-Azido-3'-deoxythymidine & Lymphoblastoid Interferon
3'-Azido-3'-deoxythymidine & Recombinant Interferon-.alpha.-2
3'-Azido-3'-deoxythymidine & Sho-Saiko-To
3'-Azido-3'-deoxythymidine (AIDS)
3'-Azido-3'deoxythymidine & Interferon .alpha.
3'-Azido-3'deoxythymidine & Nanoparticles (from human serum albumin or polyhexylcyanoacrylate)
3'-Azido-3'deoxythymidine & Recombinant Soluble CD4 & Recombinant Interferon.alpha.A
3'-Azidothymidine
3'-deoxy-3'-azidothymidine
3-azido-3-deoxythymidine
30516-87-1
399024-19-2
A2169_SIGMA
AIDS-000001
AIDS-000592
AIDS-000596
AIDS-000759
AIDS-000760
AIDS-001533
AIDS-001534
AIDS-001535
AIDS-001705
AIDS-001706
AIDS-001707
AIDS-001708
AIDS-001709
AIDS-001710
AIDS-001711
AIDS-001803
AIDS-001890
AIDS-001913
AIDS-001914
AIDS-005243
AIDS-005888
AIDS-006407
AIDS-058048
AIDS-060006
AIDS-106464
AIDS-106819
AIDS-335082
AIDS-352656
AIDS-415079
AIDS000001
AIDS000592
AIDS000596
AIDS000759
AIDS000760
AIDS001533
AIDS001534
AIDS001535
AIDS001705
AIDS001706
AIDS001707
AIDS001708
AIDS001709
AIDS001710
AIDS001711
AIDS001803
AIDS001890
AIDS001913
AIDS001914
AIDS005243
AIDS005888
AIDS006407
AIDS058048
AIDS060006
AIDS106464
AIDS106819
AIDS335082
AIDS352656
AIDS415079
antiviral
azidodeoxythymidine
Azidothymidine
AZT
AZT & CD4(178)-PE 40
AZT & Colony-stimulating factor 2
AZT & Concanavalin A (ConA)
AZT & EPO
AZT & GM-CSF
AZT & HPA
AZT & IFN.alpha.
AZT & IL-1
AZT & IL-2
AZT & IL-6
AZT & Interferon-.alpha.-2
AZT & Li & EPO
AZT & Li & GM-CSF
AZT & Li & IL-1
AZT & Li & IL-6
AZT & Lymphoblastoid Interferon
AZT & NP (from PHCA or HSA)
AZT & PM-19
AZT & rIFN.alpha.2
AZT & rsCD4 & rIFN.alpha.A
AZT & rsT4
AZT & sCD4
AZT & srCD4
AZT & SST
AZT (Antiviral)
AZT Antiviral
AZT TRANSPLACENTAL CARCINOGENESIS STUDY
AZT+PRO 140
AZT, Antiviral
AZTEC
Beta interferon(rIFN-beta seron) & 3'-Azido-3'-deoxythymidine(AZT)
BPBio1_000403
BSPBio_000365
BSPBio_003153
BW A509U
BW-A 509U
BW-A509U
BWA-509U
C07210
C10H13N5O4
CCRIS 105
CHEBI:10110
Combivir
Compound S
Cpd S
D00413
DB00495
DivK1c_000524
DRG-0004
DS-4152 & AZT
HSDB 6515
IDI1_000524
Interferon AD + 3'-azido-3'-deoxythymidine
Intron A & AZT
K7 [P Ti2 W10 O40]
KBio1_000524
KBio2_001828
KBio2_004396
KBio2_006964
KBio3_002653
KBioGR_000703
KBioSS_001828
KS-1131
Lecithinized superoxide dismutase & Thymidine, 3'-azido-3'-deoxy-
Liposomal AZT-SN-1
Liposomal AZT-SN-3
LS-1159
Met-SDF-1.beta. & Zidovudine
Met-SDF-1.beta. & AZT
Met-Stromal Cell-derived Factor-1.beta. (Human) & 3'-Azido-3'-deoxythymidine
Mixture Name
MLS000028548
MLS001055351
MLS001076358
MLS002153202
NCGC00023945-03
NCGC00023945-04
NCGC00023945-05
NCGC00178237-01
NCGC00178237-02
NINDS_000524
NSC 602670
NSC602670
PC-SOD+AZT
Prestwick3_000333
Propolis & Thymidine, 3'-azido-3'-deoxy-
Propolis+AZT
propolis?
Racemic Liposomal AZT
racemic-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
Retrovir
Retrovir (TN)
rIFN-beta seron & AZT
SMR000058351
SN-1-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
SN-3-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
SPBio_000834
SPECTRUM1502109
Spectrum2_000927
Spectrum3_001507
Spectrum4_000332
Spectrum5_001101
Spectrum_001348
Sulfated polysaccharide-peptidoglycan DS-4152 & 3'-Azido-3'-deoxythymidine
Thymidine, 3'-azido-3'-deoxy-
Thymidine, 3'-azido-3'-deoxy- & PRO 140 (Anti-CCR5 monoclonal antibody)
Trizivir
ZDV
Zidovudina [Spanish]
Zidovudine
Zidovudine (JAN/USP/INN)
ZIDOVUDINE [AZT]
Zidovudine [USAN:BAN:INN:JAN]
Zidovudine [USAN:INN:BAN:JAN]
Zidovudine+PRO 140
Zidovudinum
Zidovudinum [Latin]
ZINC03779042
ZVD
ATC-Codes:

Target

show target details
Uniprot ID:POL_HV1H2
Synonyms:
Gag-Pol polyprotein
Pr160Gag-Pol
EC-Numbers:-
Organism:HIV-1
Human immunodeficiency virus type 1
isolate HXB2 group M subtype B
PDB IDs:1A30 1BV7 1BV9 1BVE 1BVG 1BWA 1BWB 1C0T 1C0U 1C1B 1C1C 1DMP 1DTQ 1DTT 1E6J 1EP4 1ESK 1EX4 1EXQ 1FB7 1FK9 1FKO 1FKP 1G6L 1HIV 1HVH 1HVR 1HWR 1HXB 1JKH 1JLA 1JLB 1JLC 1JLE 1JLF 1JLG 1JLQ 1KLM 1LV1 1LW0 1LW2 1LWC 1LWE 1LWF 1NCP 1O1W 1ODW 1ODY 1QBR 1QBS 1QBT 1QBU 1REV 1RT1 1RT2 1RT3 1RT4 1RT5 1RT6 1RT7 1RTD 1RTH 1RTI 1RTJ 1S1T 1S1U 1S1V 1S1W 1S1X 1T05 1TAM 1TKT 1TKX 1TKZ 1TL1 1TL3 1VRT 1VRU 2HND 2HNY 2HNZ 2NPH 2OPP 2OPQ 2OPR 2OPS 2RF2 2RKI 3C6T 3C6U 3DI6 3DLE 3DLG 3DM2 3DMJ 3DOK 3DOL 3DOX 3DRP 3DRR 3DRS 3DYA 3E01 3I0R 3I0S 3PHV
Structure:
3PHV

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: