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Drug-Target Interaction

Drug

show drug details
PubChem ID:35370
Structure:
Synonyms:
"3′-azido-3′-deoxythymidine"
1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)-5-methylpyrimidine-2,4-(1H,3H
1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)-5-methylpyrimidine-2,4-(1H,3H)-dione
1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione
3′-Azido-3′-deoxythymidine
3'- Azido-3'-deoxythymidine & Granulocyte-macrophage colony-stimulating factor
3'-Azido-2',3'-Dideoxythymidine
3'-Azido-2',3'-dideoxythymidine & sCD4(soluble recombinant protein)
3'-Azido-3'-deoxythymidine
3'-Azido-3'-deoxythymidine & CD4-Pseudomonas exotoxin A hybrid
3'-Azido-3'-deoxythymidine & Concanavalin A
3'-Azido-3'-deoxythymidine & Erythropoietin
3'-Azido-3'-deoxythymidine & Heteropolyoxotungstate PM-19
3'-Azido-3'-deoxythymidine & Interleukin-1
3'-Azido-3'-deoxythymidine & Interleukin-2
3'-Azido-3'-deoxythymidine & Interleukin-6
3'-Azido-3'-deoxythymidine & Lithium & Erythropoietin
3'-Azido-3'-deoxythymidine & Lithium & Granulocyte-macrophage colony-stimulating factor
3'-Azido-3'-deoxythymidine & Lithium & Interleukin-1
3'-Azido-3'-deoxythymidine & Lithium & Interleukin-6
3'-Azido-3'-deoxythymidine & Lymphoblastoid Interferon
3'-Azido-3'-deoxythymidine & Recombinant Interferon-.alpha.-2
3'-Azido-3'-deoxythymidine & Sho-Saiko-To
3'-Azido-3'-deoxythymidine (AIDS)
3'-Azido-3'deoxythymidine & Interferon .alpha.
3'-Azido-3'deoxythymidine & Nanoparticles (from human serum albumin or polyhexylcyanoacrylate)
3'-Azido-3'deoxythymidine & Recombinant Soluble CD4 & Recombinant Interferon.alpha.A
3'-Azidothymidine
3'-deoxy-3'-azidothymidine
3-azido-3-deoxythymidine
30516-87-1
399024-19-2
A2169_SIGMA
AIDS-000001
AIDS-000592
AIDS-000596
AIDS-000759
AIDS-000760
AIDS-001533
AIDS-001534
AIDS-001535
AIDS-001705
AIDS-001706
AIDS-001707
AIDS-001708
AIDS-001709
AIDS-001710
AIDS-001711
AIDS-001803
AIDS-001890
AIDS-001913
AIDS-001914
AIDS-005243
AIDS-005888
AIDS-006407
AIDS-058048
AIDS-060006
AIDS-106464
AIDS-106819
AIDS-335082
AIDS-352656
AIDS-415079
AIDS000001
AIDS000592
AIDS000596
AIDS000759
AIDS000760
AIDS001533
AIDS001534
AIDS001535
AIDS001705
AIDS001706
AIDS001707
AIDS001708
AIDS001709
AIDS001710
AIDS001711
AIDS001803
AIDS001890
AIDS001913
AIDS001914
AIDS005243
AIDS005888
AIDS006407
AIDS058048
AIDS060006
AIDS106464
AIDS106819
AIDS335082
AIDS352656
AIDS415079
antiviral
azidodeoxythymidine
Azidothymidine
AZT
AZT & CD4(178)-PE 40
AZT & Colony-stimulating factor 2
AZT & Concanavalin A (ConA)
AZT & EPO
AZT & GM-CSF
AZT & HPA
AZT & IFN.alpha.
AZT & IL-1
AZT & IL-2
AZT & IL-6
AZT & Interferon-.alpha.-2
AZT & Li & EPO
AZT & Li & GM-CSF
AZT & Li & IL-1
AZT & Li & IL-6
AZT & Lymphoblastoid Interferon
AZT & NP (from PHCA or HSA)
AZT & PM-19
AZT & rIFN.alpha.2
AZT & rsCD4 & rIFN.alpha.A
AZT & rsT4
AZT & sCD4
AZT & srCD4
AZT & SST
AZT (Antiviral)
AZT Antiviral
AZT TRANSPLACENTAL CARCINOGENESIS STUDY
AZT+PRO 140
AZT, Antiviral
AZTEC
Beta interferon(rIFN-beta seron) & 3'-Azido-3'-deoxythymidine(AZT)
BPBio1_000403
BSPBio_000365
BSPBio_003153
BW A509U
BW-A 509U
BW-A509U
BWA-509U
C07210
C10H13N5O4
CCRIS 105
CHEBI:10110
Combivir
Compound S
Cpd S
D00413
DB00495
DivK1c_000524
DRG-0004
DS-4152 & AZT
HSDB 6515
IDI1_000524
Interferon AD + 3'-azido-3'-deoxythymidine
Intron A & AZT
K7 [P Ti2 W10 O40]
KBio1_000524
KBio2_001828
KBio2_004396
KBio2_006964
KBio3_002653
KBioGR_000703
KBioSS_001828
KS-1131
Lecithinized superoxide dismutase & Thymidine, 3'-azido-3'-deoxy-
Liposomal AZT-SN-1
Liposomal AZT-SN-3
LS-1159
Met-SDF-1.beta. & Zidovudine
Met-SDF-1.beta. & AZT
Met-Stromal Cell-derived Factor-1.beta. (Human) & 3'-Azido-3'-deoxythymidine
Mixture Name
MLS000028548
MLS001055351
MLS001076358
MLS002153202
NCGC00023945-03
NCGC00023945-04
NCGC00023945-05
NCGC00178237-01
NCGC00178237-02
NINDS_000524
NSC 602670
NSC602670
PC-SOD+AZT
Prestwick3_000333
Propolis & Thymidine, 3'-azido-3'-deoxy-
Propolis+AZT
propolis?
Racemic Liposomal AZT
racemic-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
Retrovir
Retrovir (TN)
rIFN-beta seron & AZT
SMR000058351
SN-1-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
SN-3-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
SPBio_000834
SPECTRUM1502109
Spectrum2_000927
Spectrum3_001507
Spectrum4_000332
Spectrum5_001101
Spectrum_001348
Sulfated polysaccharide-peptidoglycan DS-4152 & 3'-Azido-3'-deoxythymidine
Thymidine, 3'-azido-3'-deoxy-
Thymidine, 3'-azido-3'-deoxy- & PRO 140 (Anti-CCR5 monoclonal antibody)
Trizivir
ZDV
Zidovudina [Spanish]
Zidovudine
Zidovudine (JAN/USP/INN)
ZIDOVUDINE [AZT]
Zidovudine [USAN:BAN:INN:JAN]
Zidovudine [USAN:INN:BAN:JAN]
Zidovudine+PRO 140
Zidovudinum
Zidovudinum [Latin]
ZINC03779042
ZVD
ATC-Codes:

Target

show target details
Uniprot ID:DPOLB_HUMAN
Synonyms:
DNA polymerase beta
EC-Numbers:2.7.7.7
4.2.99.-
Organism:Homo sapiens
Human
PDB IDs:1BPX 1BPY 1BPZ 1MQ2 1MQ3 1TV9 1TVA 1ZJM 1ZJN 1ZQA 1ZQB 1ZQC 1ZQD 1ZQE 1ZQF 1ZQG 1ZQH 1ZQI 1ZQJ 1ZQK 1ZQL 1ZQM 1ZQN 1ZQO 1ZQP 1ZQQ 1ZQR 1ZQS 1ZQT 2FMP 2FMQ 2FMS 2I9G 2ISO 2ISP 2P66 2PXI 3C2K 3C2L 3C2M 3GDX 3ISB 3ISC 3ISD 7ICE 7ICF 7ICG 7ICH 7ICI 7ICJ 7ICK 7ICL 7ICM 7ICN 7ICO 7ICP 7ICQ 7ICR 7ICS 7ICT 7ICU 7ICV 8ICA 8ICB 8ICC 8ICE 8ICF 8ICG 8ICH 8ICI 8ICJ 8ICK 8ICL 8ICM 8ICN 8ICO 8ICP 8ICQ 8ICR 8ICS 8ICT 8ICU 8ICV 8ICW 8ICX 8ICY 8ICZ 9ICA 9ICB 9ICC 9ICE 9ICF 9ICG 9ICH 9ICI 9ICJ 9ICK 9ICL 9ICM 9ICN 9ICO 9ICP 9ICQ 9ICR 9ICS 9ICT 9ICU 9ICV 9ICW 9ICX 9ICY
Structure:
9ICY

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
-->20000-

References: