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Drug-Target Interaction

Drug

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PubChem ID:3510
Structure:
Synonyms:
1-methyl-n-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-1h-indazole-3-carboxamid
1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]nonan-7-yl)indazole-3-carboxamide
1-Methyl-N-(9-methyl-endo-9-azabicyclo(3.3.1)non-3-yl)-1H-indazole-3-carboxamide
107007-99-8
109889-09-0
121061-98-1
1H-Indazole-3-carboxamide, 1-methyl-N-(9-methyl-9-azabicyclo(3.3.1)non-3-yl)-, endo-
BRL 43694
BRL 43964
BRL-43694
BRL-43694A
C18H24N4O
DB00889
GRANISETRON
Granisetron base
Granisetron HCl
Granisetron hydrochloride
Granisetron Monohydrochloride
Granisetron [USAN:BAN:INN]
Granisetronum [INN-Latin]
Kytril
LS-172104
PDSP1_001266
PDSP2_001250
Sancuso
ATC-Codes:
Side-Effects:
Side-EffectFrequency
abdominal pain0.15941177
headache0.13915625
constipation0.11103705
asthenia0.095517226
somnolence0.08583334
diarrhea0.065827586
anemia0.058399994
pain0.0574
fever0.044600002
dyspepsia0.042052638
leukocytosis0.038333334
insomnia0.0356
bradycardia0.029
urinary tract infection0.028666668
infection0.027666666
dizziness0.027200002
anxiety0.0252
hypotension0.0252
hypertension0.022599999
flatulence0.02
coughing0.018333333
hypokalemia0.01
liver function tests abnormal0.01
paresthesia0.01
malaise0.01
migraine0.01
jaundice0.01
tremor0.01
chills0.01
nervousness0.01
dry mouth0.01
pruritus0.01
sweating0.01
agitation0.01
syncope0.01
dysuria0.01
hiccup0.01
dyspnea0.01
rash0.01
abnormal vision0.0010
vertigo0.0010
chest pain0.0010
thrombocytopenia0.0010
tachycardia0.0010
vomiting0.0010
coma0.0010
allergic reaction0.0010
urinary incontinence0.0010
hyperphosphatemia0.0010
atrial fibrillation0.0010
arrhythmia0.0010
angina pectoris0.0010
photosensitivity0.0010
edema0.0010
grand mal convulsion0.0010
hyponatremia0.0010
bilirubinemia0.0010
hepatic coma0.0010
gastrointestinal haemorrhage0.0010
leukopenia0.0010
melena0.0010
epistaxis0.0010
eosinophilia0.0010
palpitation0.0010
postural hypotension0.0010
puncture0.0010
sinusitis0.0010
rhinitis0.0010
alopecia0
anaphylaxis0
shortness of breath0
hypersensitivity0
dermatitis0
urticaria0
depersonalization0
sinus bradycardia0

Target

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Uniprot ID:5HT5A_HUMAN
Synonyms:
5-HT-5
5-HT-5A
5-hydroxytryptamine receptor 5A
Serotonin receptor 5A
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: