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Drug-Target Interaction

Drug

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PubChem ID:3475
Structure:
Synonyms:
1-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea
1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea
1-(3-Azabicyclo[3.3.0]oct-3-yl)-3-p-tolylsulphonylurea
1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea
21187-98-4
AB00053165
Benzenesulfonamide, N-(((hexahydrocyclopenta(c)pyrrol-2(1H)-yl)amino)carbonyl)-4-methyl-
BPBio1_000699
BRN 1657836
BSPBio_000635
BSPBio_003304
C15H21N3O3S
CHEBI:31654
D01599
DB01120
Diaikron
Diamicron
DivK1c_006966
EINECS 244-260-5
G2167_SIGMA
Gliclazida [INN-Spanish]
GLICLAZIDE
Gliclazide (JAN/INN)
Gliclazide [BAN:DCF:INN:JAN]
Gliclazide [BAN:INN:DCF:JAN]
Gliclazidum [INN-Latin]
Gliklazid
Glimicron
Glimicron (TN)
Glyclazide
KBio1_001910
KBio2_001958
KBio2_004526
KBio2_007094
KBio3_002806
KBioGR_001096
KBioSS_001958
LS-160299
MLS001215197
MLS001304077
N-(4-Methylbenzenesulfonyl)-N'-(3-azabicyclo(3.3.0)oct-3-yl)urea
N-(hexahydrocyclopenta[c]pyrrol-2(1H)-ylcarbamoyl)-4-methylbenzenesulfonam
N-(hexahydrocyclopenta[c]pyrrol-2(1H)-ylcarbamoyl)-4-methylbenzenesulfonamide
N-[(hexahydrocyclopenta[c]pyrrol-2(1H)-ylamino)carbonyl]-4-methylbenzenesulfonamide
NCGC00095107-01
NCGC00095107-02
NCGC00095107-03
NCGC00095107-04
NCGC00095107-05
NCGC00095107-06
Nordialex
Prestwick0_000558
Prestwick1_000558
Prestwick2_000558
Prestwick3_000558
Prestwick_869
S 1702
S 852
S-1702
S-852
SE 1702
SMR000542971
SPBio_002556
SpecPlus_000870
SPECTRUM1504145
SPECTRUM1505013
Spectrum3_001862
Spectrum4_000598
Spectrum5_000753
Spectrum_001478
ST076805
Urea, 1-(hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)-
ATC-Codes:
Side-Effects:
Side-EffectFrequency
abdominal pain0.0010
hypoglycaemia0.0010
jaundice0.0010
allergic vasculitis0.0010
liver failure0.0010
coma0.0010
erythema0.0010
pancytopenia0.0010
constipation0.0010
vomiting0.0010
hepatitis0.0010
urticaria0.0010
pruritus0.0010
diarrhea0.0010
haemolytic anaemia0.0010
pyrexia0.0010
agranulocytosis0.0010
dyspepsia0.0010
rash0.0010
pancreatitis acute0.0010
nausea0.0010
thrombocytopenia0.0010
pharyngitis0
pneumonia0
skin ulcer0
sinusitis0
increased salivation0
polyuria0
porphyria0
melena0
retinopathy0
rhinitis0
paresthesia0
mastitis0
menstrual disorder0
fungal infection0
myocardial infarction0
nail disorder0
tumor0
nervousness0
neuralgia0
nocturia0
otitis media0
pain0
palpitations0
weakness0
leukopenia0
cerebrovascular accident0
sweating0
hyperkeratosis0
bone pain0
dry skin0
disorder of lipid metabolism0
malnutrition0
malaise0
myalgia0
photosensitivity0
neuropathy0
insomnia0
hearing loss0
breast neoplasm0
allergic reaction0
cataract0
dry mouth0
weight gain0
tachycardia0
tendinitis0
thrombophlebitis0
onychomycosis0
tinnitus0
tooth disorder0
toothache0
tracheitis0
upper respiratory tract infection0
urinary tract infection0
vaginitis0
viral infection0
abnormal vision0
renal insufficiency0
leg pain0
malformations0
conjunctivitis0
coronary artery disease0
cough0
cystitis0
dermatitis0
fungal dermatitis0
diplopia0
dizziness0
somnolence0
duodenal ulcer0
carpal tunnel syndrome0
dyspnea0
eczema0
edema0
confusion0
colitis0
chest pain0
albuminuria0
anemia0
angina pectoris0
anxiety0
arteritis0
arthralgia0
arthritis0
asthenia0
asthma0
back pain0
bronchitis0
bursitis0
carcinoma0
cerebrovascular disorder0
epistaxis0
esophagitis0
hyperlipidemia0
hypersensitivity0
hypertension0
hypertriglyceridemia0
hypopituitarism0
hypotension0
hypothyroidism0
impotence0
infection0
heart disease0
arthrosis0
kidney calculus0
nephropathy0
acute renal failure0
hypercholesterolemia0
hernia0
hepatomegaly0
fatigue0
fecal incontinence0
anal fissure0
flatulence0
gastritis0
gastroenteritis0
gastroesophageal reflux0
glaucoma0
glycosuria0
gout0
headache0
heart failure0
hemorrhage0
hemorrhoids0
renal cyst0

Target

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Uniprot ID:ALBU_HUMAN
Synonyms:
Serum albumin
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:1AO6 1BJ5 1BKE 1BM0 1E78 1E7A 1E7B 1E7C 1E7E 1E7F 1E7G 1E7H 1E7I 1GNI 1GNJ 1H9Z 1HA2 1HK1 1HK2 1HK3 1HK4 1HK5 1N5U 1O9X 1TF0 1UOR 1YSX 2BX8 2BXA 2BXB 2BXC 2BXD 2BXE 2BXF 2BXG 2BXH 2BXI 2BXK 2BXL 2BXM 2BXN 2BXO 2BXP 2BXQ 2ESG 2I2Z 2I30 2VDB 2VUE 2VUF 3B9L 3B9M 3CX9
Structure:
3CX9

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: