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Drug-Target Interaction

Drug

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PubChem ID:3372
Structure:
Synonyms:
"10-(3'-(4""-(beta-hydroxyethyl)-1""-piperazinyl)-propyl)-3-trifluoromethylphenothiazine"
1-(2-Hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine
1-(2-Hydroxyethyl)-4-[3-(trifluoromethyl-10-phenothiazinyl)propyl]piperazine
1-Piperazineethanol,
1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-
1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)- (9CI)
1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)-
1-Piperazineethanol, 4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-
10-(3'-(4"-(beta-Hydroxyethyl)-1"-piperazinyl)-propyl)-3-trifluoromethylphenothiazine
10-(3-(2-Hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine
146-56-5 (DLHYDROCHLORIDE)
2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethanol
2-(Trifluoromethyl)-10-(3-(1-(beta-hydroxyethyl)-4-pipe razinyl)propyl)phenothiazine
2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol
2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol dihydrochloride
4-(3-(-Trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol
4-(3-(2-(Trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-1-piperazineethanol
4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)-1-Piperazineethanol
4-(3-(2-Trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol
4-[3-(2-Trifluoromethyl-10-phenothiazyl)-propyl]-1-piperazineethanol
47646-09-3
69-23-8
A 4077
AB00053587
AIDS-015551
AIDS015551
Anatensol
Biomol-NT_000023
BPBio1_000352
BPBio1_001187
BSPBio_000320
BSPBio_003100
C07010
C22H26F3N3OS
Calmansial
CAS-146-56-5
CHEBI:5123
ChemDiv1_024180
cMAP_000035
Dapotum
DB00623
DivK1c_000511
EINECS 200-702-9
Elinol
Flufenazin
Flufenazina
Flufenazina [DCIT]
Fluorfenazine
Fluorophenazine
Fluorphenazine
Fluphenazine
Fluphenazine Decanoate
Fluphenazine dihydrochloride
Fluphenazine Hcl
Fluphenazine Hydrochloride
Fluphenazine [INN:BAN]
Fluphenazinum
Fluphenazinum [INN-Latin]
Ftorphenazine
HSDB 3334
IDI1_000511
KBio1_000511
KBio2_000769
KBio2_002386
KBio2_003337
KBio2_004954
KBio2_005905
KBio2_007522
KBio3_002320
KBio3_002865
KBioGR_001375
KBioGR_002386
KBioSS_000769
KBioSS_002391
Lopac-F-4765
Lopac0_000555
LS-112565
Lyogen
Moditen (Tabl or elixir)
NCGC00015436-01
NCGC00015436-02
NCGC00015436-03
NCGC00024429-03
NCGC00024429-04
nchembio873-comp68
NINDS_000511
NSC 62323
NSC62323
Pacinol
Phenothiazine, 10-(3-(4-(2-hydroxyethyl)-1-piperazinyl)propyl)-2-(trifluoromethyl)-
Phthorphenazine
Prestwick0_000320
Prestwick1_000320
Prestwick2_000320
Prestwick3_000320
Probes1_000254
Probes2_000295
Prolixin
S94
Sevinol
Siqualine
Siqualon
SPBio_001277
SPBio_002539
Spectrum2_001199
Spectrum3_001420
Spectrum4_000828
Spectrum5_001536
Spectrum_000289
SQ 4918
SR-01000003048-5
STK050763
Triflumethazine
Valamina
Vespazine
ATC-Codes:
Side-Effects:
Side-EffectFrequency
renal insufficiency0.0
tachycardia0.0
perspiration0.0
cerebrovascular stroke0.0
salivation0.0
seizure0.0
seborrhea0.0
purpura0.0
itching0.0
polyuria0.0
pneumonitis0.0
pheochromocytoma0.0
paralytic ileus0.0
pancytopenia0.0
erythema0.0
upper respiratory infection0.0
urticaria0.0
allergic reactions0.0
diaphoresis0.0
paralysis0.0
dementia0.0
photosensitivity0.0
blurred vision0.0
autonomic instability0.0
peripheral edema0.0
restlessness0.0
dry mouth0.0
vomiting0.0
ventricular tachycardia0.0
ventricular fibrillation0.0
nausea0.0
nasal congestion0.0
agranulocytosis0.0
eosinophilia0.0
edema0.0
eczema0.0
drowsiness0.0
exfoliative dermatitis0.0
corneal opacities0.0
constipation0.0
coma0.0
transient ischemic attacks0.0
asthma0.0
arrhythmias0.0
loss of appetite0.0
angioneurotic edema0.0
fecal impaction0.0
fever0.0
glaucoma0.0
mitral insufficiency0.0
systemic lupus erythematosus0.0
leukopenia0.0
leukocytosis0.0
acute renal failure0.0
jaundice0.0
syndrome of inappropriate antidiuretic hormone0.0
hypotension0.0
gynecomastia0.0
headache0.0
cardiac arrest0.0
hepatitis0.0
hypertension0.0
hyponatremia0.0
excitement0
tremor0
renal failure0
tardive dyskinesia0
dysphagia0
dyspnea0
spasm0
parkinson0
dyskinesia0
stupor0

Target

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Uniprot ID:CP1A2_HUMAN
Synonyms:
CYPIA2
Cytochrome P450 1A2
P(3)450
P450 4
P450-P3
EC-Numbers:1.14.14.1
Organism:Homo sapiens
Human
PDB IDs:2HI4
Structure:
2HI4

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: