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Drug-Target Interaction

Drug

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PubChem ID:3119958
Structure:
Synonyms:
()-oxazepam hemisuccinate sodium salt
7-(2-hydroxy-3-naphthalen-2-yloxypropyl)-3-methyl-8-sulfanylidene-9H-purin
7-[2-hydroxy-3-(2-naphthyloxy)propyl]-3-methyl-8-sulfanyl-3,7-dihydro-1H-purine-2,6-dione
7-[2-hydroxy-3-(naphthalen-2-yloxy)propyl]-3-methyl-8-sulfanyl-3,7-dihydro-1H-purine-2,6-dione
AB00684231-01
AC1MJXRO
AG-690/12243056
BAS 00843967
CHEBI:441406
CHEMBL203324
CID3119958
EU-0037392
HMS1548D14
MolPort-000-754-189
MolPort-001-902-214
Oprea1_325811
Oprea1_394678
STK030937
STK566784
STOCK1S-14031
TimTec1_005008

Target

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Uniprot ID:PDE5A_HUMAN
Synonyms:
CGB-PDE
cGMP-binding cGMP-specific phosphodiesterase
cGMP-specific 3',5'-cyclic phosphodiesterase
EC-Numbers:3.1.4.35
Organism:Homo sapiens
Human
PDB IDs:1RKP 1T9R 1T9S 1TBF 1UDT 1UDU 1UHO 1XOZ 1XP0 2CHM 2H40 2H42 2H44 3B2R 3BJC 3HC8 3HDZ
Structure:
3HDZ

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--8700-

References: