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Drug-Target Interaction

Drug

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PubChem ID:3081361
Structure:
Synonyms:
2ivu
338992-00-0
4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]q
4-BROMO-2-FLUORO-N-[(4E)-6-METHOXY-7-[(1-METHYLPIPERIDIN-4-YL)METHOXY]QUINAZOLIN-4(1H)-YLIDENE]ANILINE
4-Quninazolinamine, N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-
443913-73-3
AZD-6474
C452423
CHEBI:49960
D06407
LS-184394
N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-4-quinazolinamine
N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine
N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
NCGC00167513-01
vande-tanib
Vandetanib
Vandetanib (JAN/INN)
Vandetanib [INN]
Zactima
Zactima, ZD6474
ZD 6474
ZD-6474
ZD6
ZD6474

Target

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Uniprot ID:PLK1_HUMAN
Synonyms:
PLK-1
Polo-like kinase 1
Serine/threonine-protein kinase 13
Serine/threonine-protein kinase PLK1
STPK13
EC-Numbers:2.7.11.21
Organism:Homo sapiens
Human
PDB IDs:1Q4K 1Q4O 1UMW 2OGQ 2OJX 2OU7 2OWB 2RKU 2V5Q 3BZI 3C5L 3FC2 3FVH 3HIH 3HIK
Structure:
3HIK

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: