Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Drug-Target Interaction

Drug

show drug details
PubChem ID:3081361
Structure:
Synonyms:
2ivu
338992-00-0
4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]q
4-BROMO-2-FLUORO-N-[(4E)-6-METHOXY-7-[(1-METHYLPIPERIDIN-4-YL)METHOXY]QUINAZOLIN-4(1H)-YLIDENE]ANILINE
4-Quninazolinamine, N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-
443913-73-3
AZD-6474
C452423
CHEBI:49960
D06407
LS-184394
N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methyl-4-piperidinyl)methoxy)-4-quinazolinamine
N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine
N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
NCGC00167513-01
vande-tanib
Vandetanib
Vandetanib (JAN/INN)
Vandetanib [INN]
Zactima
Zactima, ZD6474
ZD 6474
ZD-6474
ZD6
ZD6474

Target

show target details
Uniprot ID:FYN_HUMAN
Synonyms:
p59-Fyn
Proto-oncogene tyrosine-protein kinase Fyn
Protooncogene Syn
SLK
EC-Numbers:2.7.10.2
Organism:Homo sapiens
Human
PDB IDs:1A0N 1AOT 1AOU 1AVZ 1AZG 1EFN 1FYN 1G83 1M27 1NYF 1NYG 1SHF 1ZBJ 2DQ7
Structure:
2DQ7

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
-360--
-5700--

References: