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Drug-Target Interaction

Drug

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PubChem ID:3052776
Structure:
Synonyms:
(1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine
(1R)-N-prop-2-ynyl-2,3-dihydro-1H-inden-1-amine
(R)-N-2-Propynyl-1-indanamine
1-Indanamine, N-2-propynyl-, (R)-
136236-51-6
1H-Inden-1-amine, 2,3-dihydro-N-2-propynyl-, (1R)
AC-723
AC1MHJZT
Azilect (TN)
CHEBI:45357
CHEMBL887
D08469
DB01367
HMS3264K12
I06-1870
LS-186771
LS-187776
N-PROPARGYL-1(R)-AMINONDAN
NCGC00168774-01
RAS
Rasagiline
Rasagiline (INN)
Rasagiline [INN]
UNII-003N66TS6T
ZINC19875504
ATC-Codes:
Side-Effects:
Side-EffectFrequency
gastrointestinal hemorrhage1.0
hematuria1.0
neuropathy1.0
cough1.0
asthenia1.0
anxiety1.0
abnormal gait1.0
tremor1.0
bundle branch block1.0
urinary incontinence1.0
headache0.14
dyspepsia0.07
arthralgia0.07
flu syndrome0.05
rhinitis0.03
gastroenteritis0.03
fever0.03
conjunctivitis0.03
ecchymosis0.02
vertigo0.02
neck pain0.02
malaise0.02
arthritis0.02
paresthesia0.012499999
agitation0.01
kidney calculus0.01
acute kidney failure0.01
keratitis0.01
hypocalcemia0.01
mouth ulceration0.01
vaginal hemorrhage0.01
glaucoma0.01
eczema0.01
heart failure0.01
hemiplegia0.01
hemorrhage0.01
migraine0.01
muscle atrophy0.01
pneumothorax0.01
ptosis0.01
chills0.01
psychosis0.01
emphysema0.01
retinal degeneration0.01
urticaria0.01
convulsion0.01
urinary retention0.01
stomach ulcer0.01
polyuria0.01
vaginitis0.01
myocardial infarct0.01
neuritis0.01
neurosis0.01
nocturia0.01
bone necrosis0.01
personality disorder0.01
phlebitis0.01
pleural effusion0.01
ventricular tachycardia0.01
stomatitis0.01
flank pain0.01
apnea0.01
esophageal ulcer0.01
dysarthria0.01
visual field defect0.01
dementia0.01
diplopia0.01
blepharitis0.01
eye pain0.01
vaginal moniliasis0.01
deafness0.01
photosensitivity0.01
dysesthesia0.01
dysmenorrhea0.01
aphasia0.01
colitis0.01
esophagitis0.01
facial paralysis0.01
macrocytic anemia0.01
dysuria0.01
fecal incontinence0.01
deep thrombophlebitis0.01
edema0.0054999995
arthrosis0.0040
amenorrhea0.0010
blindness0.0010
priapism0.0010
ventricular fibrillation0.0010
cerebral ischemia0.0010
thrombocythemia0.0010
manic depressive reaction0.0010
lung fibrosis0.0010
purpura0.0010
retinal detachment0.0010
retinal hemorrhage0.0010
vestibular disorder0.0010
hydroureter0.0010
arrhythmia0.0010
strabismus0.0010
cerebral hemorrhage0.0010
hemorrhagic gastritis0.0010
intestinal perforation0.0010
photophobia0.0010
hematemesis0.0010
jaundice0.0010
leukoderma0.0010
av block complete0.0010
interstitial pneumonia0.0010
megacolon0.0010
melena0.0010
av block second degree0.0010
delirium0.0010
bigeminy0.0010
epididymitis0.0010
neuralgia0.0010
gynecomastia0.0010
exfoliative dermatitis0.0010
myelitis0.0010
skin carcinoma0
liver function tests abnormal0
vomiting0
weight loss0
dry mouth0
manic0
emotional lability0
abdominal pain0
apathy0
stupor0
allergic reaction0
tenosynovitis0
dizziness0
diarrhea0
delusions0
dysphagia0
decreased libido0
constipation0
confusion0
chest pain0
bursitis0
ataxia0
asthma0
anorexia0
angina pectoris0
anemia0
amnesia0
alopecia0
somnolence0
dyskinesia0
dyspnea0
syncope0
sweating0
cerebrovascular accident0
skin ulcer0
pruritus0
nausea0
leukopenia0
leg cramps0
infection0
impotence0
postural hypotension0
hernia0
hallucinations0
gingivitis0
rash0
epistaxis0
albuminuria0

Target

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Uniprot ID:CP1A2_HUMAN
Synonyms:
CYPIA2
Cytochrome P450 1A2
P(3)450
P450 4
P450-P3
EC-Numbers:1.14.14.1
Organism:Homo sapiens
Human
PDB IDs:2HI4
Structure:
2HI4

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: