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Drug-Target Interaction

Drug

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PubChem ID:3038525
Structure:
Synonyms:
209410-46-8
5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido(1,6-b)pyridazin-6-one
6H-Pyrimido(1,6-b)pyridazin-6-one,
6H-Pyrimido(1,6-b)pyridazin-6-one, 5-(2,6-dichlorophenyl)-2-((2,4-difluorophenyl)thio)-
VX-745
VX745, VX-745
ZINC13493055

Target

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Uniprot ID:PLK1_HUMAN
Synonyms:
PLK-1
Polo-like kinase 1
Serine/threonine-protein kinase 13
Serine/threonine-protein kinase PLK1
STPK13
EC-Numbers:2.7.11.21
Organism:Homo sapiens
Human
PDB IDs:1Q4K 1Q4O 1UMW 2OGQ 2OJX 2OU7 2OWB 2RKU 2V5Q 3BZI 3C5L 3FC2 3FVH 3HIH 3HIK
Structure:
3HIK

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: