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Drug-Target Interaction

Drug

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PubChem ID:3038525
Structure:
Synonyms:
209410-46-8
5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido(1,6-b)pyridazin-6-one
6H-Pyrimido(1,6-b)pyridazin-6-one,
6H-Pyrimido(1,6-b)pyridazin-6-one, 5-(2,6-dichlorophenyl)-2-((2,4-difluorophenyl)thio)-
VX-745
VX745, VX-745
ZINC13493055

Target

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Uniprot ID:MP2K4_HUMAN
Synonyms:
c-Jun N-terminal kinase kinase 1
Dual specificity mitogen-activated protein kinase kinase 4
JNK-activating kinase 1
JNKK
MAP kinase kinase 4
SAPK/ERK kinase 1
SEK1
EC-Numbers:2.7.12.2
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: