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Drug-Target Interaction

Drug

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PubChem ID:3038525
Structure:
Synonyms:
209410-46-8
5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido(1,6-b)pyridazin-6-one
6H-Pyrimido(1,6-b)pyridazin-6-one,
6H-Pyrimido(1,6-b)pyridazin-6-one, 5-(2,6-dichlorophenyl)-2-((2,4-difluorophenyl)thio)-
VX-745
VX745, VX-745
ZINC13493055

Target

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Uniprot ID:MAPK2_HUMAN
Synonyms:
MAP kinase-activated protein kinase 2
MAPK-activated protein kinase 2
MAPKAP kinase 2
MAPKAPK-2
MK2
EC-Numbers:2.7.11.1
Organism:Homo sapiens
Human
PDB IDs:1KWP 1NXK 1NY3 2JBO 2JBP 2OKR 2ONL 2OZA 2P3G 2PZY 3FPM 3FYJ 3FYK
Structure:
3FYK

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: