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Drug-Target Interaction

Drug

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PubChem ID:3038525
Structure:
Synonyms:
209410-46-8
5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido(1,6-b)pyridazin-6-one
6H-Pyrimido(1,6-b)pyridazin-6-one,
6H-Pyrimido(1,6-b)pyridazin-6-one, 5-(2,6-dichlorophenyl)-2-((2,4-difluorophenyl)thio)-
VX-745
VX745, VX-745
ZINC13493055

Target

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Uniprot ID:GSK3B_HUMAN
Synonyms:
Glycogen synthase kinase-3 beta
GSK-3 beta
EC-Numbers:2.7.11.26
Organism:Homo sapiens
Human
PDB IDs:1GNG 1H8F 1I09 1J1B 1J1C 1O9U 1PYX 1Q3D 1Q3W 1Q41 1Q4L 1Q5K 1R0E 1UV5 2JDO 2JDR 2JLD 2O5K 2OW3 2UW9 3CQU 3CQW 3DU8 3E87 3E88 3E8D 3F7Z 3F88
Structure:
3F88

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: