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Drug-Target Interaction

Drug

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PubChem ID:3038525
Structure:
Synonyms:
209410-46-8
5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido(1,6-b)pyridazin-6-one
6H-Pyrimido(1,6-b)pyridazin-6-one,
6H-Pyrimido(1,6-b)pyridazin-6-one, 5-(2,6-dichlorophenyl)-2-((2,4-difluorophenyl)thio)-
VX-745
VX745, VX-745
ZINC13493055

Target

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Uniprot ID:FGFR1_HUMAN
Synonyms:
Basic fibroblast growth factor receptor 1
bFGF-R
c-fgr
CD331
FGFR-1
Fms-like tyrosine kinase 2
EC-Numbers:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:1AGW 1CVS 1EVT 1FGI 1FGK 1FQ9 1XR0 2CR3 2FGI 3C4F 3GQI 3GQL
Structure:
3GQL

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: