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Drug-Target Interaction

Drug

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PubChem ID:3038525
Structure:
Synonyms:
209410-46-8
5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido(1,6-b)pyridazin-6-one
6H-Pyrimido(1,6-b)pyridazin-6-one,
6H-Pyrimido(1,6-b)pyridazin-6-one, 5-(2,6-dichlorophenyl)-2-((2,4-difluorophenyl)thio)-
VX-745
VX745, VX-745
ZINC13493055

Target

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Uniprot ID:FAK2_HUMAN
Synonyms:
CADTK
CAK beta
Calcium-dependent tyrosine kinase
Cell adhesion kinase beta
FADK 2
Focal adhesion kinase 2
Proline-rich tyrosine kinase 2
Protein tyrosine kinase 2 beta
RAFTK
Related adhesion focal tyrosine kinase
EC-Numbers:2.7.10.2
Organism:Homo sapiens
Human
PDB IDs:2FO6 3CC6 3ET7 3FZO 3FZP 3FZR 3FZS 3FZT 3GM1 3GM2 3GM3 3H3C
Structure:
3H3C

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: