Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Drug-Target Interaction

Drug

show drug details
PubChem ID:3038525
Structure:
Synonyms:
209410-46-8
5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido(1,6-b)pyridazin-6-one
6H-Pyrimido(1,6-b)pyridazin-6-one,
6H-Pyrimido(1,6-b)pyridazin-6-one, 5-(2,6-dichlorophenyl)-2-((2,4-difluorophenyl)thio)-
VX-745
VX745, VX-745
ZINC13493055

Target

show target details
Uniprot ID:CDK5_HUMAN
Synonyms:
Cell division protein kinase 5
Cyclin-dependent kinase 5
Serine/threonine-protein kinase PSSALRE
Tau protein kinase II catalytic subunit
TPKII catalytic subunit
EC-Numbers:2.7.11.22
Organism:Homo sapiens
Human
PDB IDs:1H4L 1LFR 1UNG 1UNH 1UNL
Structure:
1UNL

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: