Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Drug-Target Interaction

Drug

show drug details
PubChem ID:3038525
Structure:
Synonyms:
209410-46-8
5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido(1,6-b)pyridazin-6-one
6H-Pyrimido(1,6-b)pyridazin-6-one,
6H-Pyrimido(1,6-b)pyridazin-6-one, 5-(2,6-dichlorophenyl)-2-((2,4-difluorophenyl)thio)-
VX-745
VX745, VX-745
ZINC13493055

Target

show target details
Uniprot ID:BTK_HUMAN
Synonyms:
Agammaglobulinaemia tyrosine kinase
ATK
B-cell progenitor kinase
BPK
Bruton tyrosine kinase
Tyrosine-protein kinase BTK
EC-Numbers:2.7.10.2
Organism:Homo sapiens
Human
PDB IDs:1AWW 1AWX 1B55 1BTK 1BWN 1K2P 1QLY 2GE9 2Z0P
Structure:
2Z0P

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: