Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Drug-Target Interaction

Drug

show drug details
PubChem ID:3038525
Structure:
Synonyms:
209410-46-8
5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido(1,6-b)pyridazin-6-one
6H-Pyrimido(1,6-b)pyridazin-6-one,
6H-Pyrimido(1,6-b)pyridazin-6-one, 5-(2,6-dichlorophenyl)-2-((2,4-difluorophenyl)thio)-
VX-745
VX745, VX-745
ZINC13493055

Target

show target details
Uniprot ID:AKT1_HUMAN
Synonyms:
C-AKT
PKB
Protein kinase B
RAC-alpha serine/threonine-protein kinase
RAC-PK-alpha
EC-Numbers:2.7.11.1
Organism:Homo sapiens
Human
PDB IDs:1H10 1UNP 1UNQ 1UNR 2UVM 2UZR 2UZS 3CQU 3CQW
Structure:
3CQW

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: