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Drug-Target Interaction

Drug

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PubChem ID:3038525
Structure:
Synonyms:
209410-46-8
5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido(1,6-b)pyridazin-6-one
6H-Pyrimido(1,6-b)pyridazin-6-one,
6H-Pyrimido(1,6-b)pyridazin-6-one, 5-(2,6-dichlorophenyl)-2-((2,4-difluorophenyl)thio)-
VX-745
VX745, VX-745
ZINC13493055

Target

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Uniprot ID:ACVR1_HUMAN
Synonyms:
Activin receptor type I
Activin receptor type-1
Activin receptor-like kinase 2
ACTR-I
ALK-2
Serine/threonine-protein kinase receptor R1
SKR1
TGF-B superfamily receptor type I
TSR-I
EC-Numbers:2.7.11.30
Organism:Homo sapiens
Human
PDB IDs:3H9R
Structure:
3H9R

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: