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Drug-Target Interaction

Drug

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PubChem ID:3038522
Structure:
Synonyms:
(4-(6-Methoxy-7-(3-piperidylpropoxy)quinazolin-4-yl)piperazinyl)-N-(4-(met
(4-(6-Methoxy-7-(3-piperidylpropoxy)quinazolin-4-yl)piperazinyl)-N-(4-(methylethoxy)phenyl)carboxamide
1-Piperazinecarboxamide, 4-(6-methoxy-7-(3-(1-piperidinyl)propoxy)-4-quinazolinyl)-N-(4-(1-methylethoxy)phenyl)-
387867-13-2
AC-1659
AC1MI50F
CHEMBL124660
CT 53518
CT-53518
CT53518
D06005
EC-000.2262
HMS3264G08
I14-1975
Kinome_3320
MLN 518
MLN-0518
MLN-518
MLN518, CT53518
NCGC00241097-01
NCGC00241097-02
NSC726292
S1043_Selleck
Tandutinib
Tandutinib (USAN/INN)
Tandutinib-Supplied by Selleck Chemicals
UNII-E1IO3ICJ9A

Target

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Uniprot ID:SRC_HUMAN
Synonyms:
c-Src
p60-Src
pp60c-src
Proto-oncogene tyrosine-protein kinase Src
EC-Numbers:2.7.10.2
Organism:Homo sapiens
Human
PDB IDs:1A07 1A08 1A09 1A1A 1A1B 1A1C 1A1E 1FMK 1HCS 1HCT 1KSW 1O41 1O42 1O43 1O44 1O45 1O46 1O47 1O48 1O49 1O4A 1O4B 1O4C 1O4D 1O4E 1O4F 1O4G 1O4H 1O4I 1O4J 1O4K 1O4L 1O4M 1O4N 1O4O 1O4P 1O4Q 1O4R 1SHD 1Y57 1YI6 1YOJ 1YOL 1YOM 2BDF 2BDJ 2H8H 2SRC
Structure:
2SRC

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
--30-
->10000--

References: