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Drug-Target Interaction

Drug

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PubChem ID:3038522
Structure:
Synonyms:
(4-(6-Methoxy-7-(3-piperidylpropoxy)quinazolin-4-yl)piperazinyl)-N-(4-(met
(4-(6-Methoxy-7-(3-piperidylpropoxy)quinazolin-4-yl)piperazinyl)-N-(4-(methylethoxy)phenyl)carboxamide
1-Piperazinecarboxamide, 4-(6-methoxy-7-(3-(1-piperidinyl)propoxy)-4-quinazolinyl)-N-(4-(1-methylethoxy)phenyl)-
387867-13-2
AC-1659
AC1MI50F
CHEMBL124660
CT 53518
CT-53518
CT53518
D06005
EC-000.2262
HMS3264G08
I14-1975
Kinome_3320
MLN 518
MLN-0518
MLN-518
MLN518, CT53518
NCGC00241097-01
NCGC00241097-02
NSC726292
S1043_Selleck
Tandutinib
Tandutinib (USAN/INN)
Tandutinib-Supplied by Selleck Chemicals
UNII-E1IO3ICJ9A

Target

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Uniprot ID:MET_HUMAN
Synonyms:
c-Met
Hepatocyte growth factor receptor
HGF receptor
HGF/SF receptor
Met proto-oncogene tyrosine kinase
Scatter factor receptor
SF receptor
EC-Numbers:2.7.10.1
Organism:Homo sapiens
Human
PDB IDs:1FYR 1R0P 1R1W 1SHY 1SSL 1UX3 2G15 2RFN 2RFS 2UZX 2UZY 2WD1 2WGJ 3BUX 3CE3 3CTH 3CTJ 3EFJ 3EFK 3F66 3F82
Structure:
3F82

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: