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Drug-Target Interaction

Drug

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PubChem ID:3038522
Structure:
Synonyms:
(4-(6-Methoxy-7-(3-piperidylpropoxy)quinazolin-4-yl)piperazinyl)-N-(4-(met
(4-(6-Methoxy-7-(3-piperidylpropoxy)quinazolin-4-yl)piperazinyl)-N-(4-(methylethoxy)phenyl)carboxamide
1-Piperazinecarboxamide, 4-(6-methoxy-7-(3-(1-piperidinyl)propoxy)-4-quinazolinyl)-N-(4-(1-methylethoxy)phenyl)-
387867-13-2
AC-1659
AC1MI50F
CHEMBL124660
CT 53518
CT-53518
CT53518
D06005
EC-000.2262
HMS3264G08
I14-1975
Kinome_3320
MLN 518
MLN-0518
MLN-518
MLN518, CT53518
NCGC00241097-01
NCGC00241097-02
NSC726292
S1043_Selleck
Tandutinib
Tandutinib (USAN/INN)
Tandutinib-Supplied by Selleck Chemicals
UNII-E1IO3ICJ9A

Target

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Uniprot ID:LCK_HUMAN
Synonyms:
LSK
Lymphocyte cell-specific protein-tyrosine kinase
p56-LCK
Proto-oncogene tyrosine-protein kinase LCK
T cell-specific protein-tyrosine kinase
EC-Numbers:2.7.10.2
Organism:Homo sapiens
Human
PDB IDs:1BHF 1BHH 1CWD 1CWE 1FBZ 1H92 1IJR 1KIK 1LCJ 1LCK 1LKK 1LKL 1Q68 1Q69 1QPC 1QPD 1QPE 1QPJ 1X27 2IIM 2OF2 2OF4 2OFU 2OFV 2OG8 2PL0 2ZM1 2ZM4 2ZYB 3B2W 3BRH 3BYM 3BYO 3BYS 3BYU 3LCK
Structure:
3LCK

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
->10000--

References: