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Drug-Target Interaction

Drug

show drug details
PubChem ID:3019
Structure:
Synonyms:
2H-1,2, 4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
2H-1,2, 4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide;
2H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide
364-98-7
7-Chloro-3-methyl-1lambda~4~,2,4-benzothiadiazin-1-ol 1-oxide
7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
7-chloro-3-methyl-4H-1
7-chloro-3-methyl-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide
7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido
7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido [Italian]
AC1L1EZN
AIDS-159927
AIDS159927
Aroglycem
Bio1_000036
Bio1_000525
Bio1_001014
Bio2_000027
Bio2_000507
BPBio1_000016
BRD-K73109821-001-05-2
BSPBio_000014
BSPBio_001307
BSPBio_002290
C06949
C8H7ClN2O2S
CAS-364-98-7
CBiol_001750
CCG-101062
CCG-204497
CHEBI:4495
CHEMBL181
CPD000058392
D 9035
D00294
D003981
D9035_SIGMA
DB01119
Diazossido
Diazossido [DCIT]
Diazossido [Italian]
Diazoxide
Diazoxide (JAN/USP/INN)
Diazoxide [USAN:BAN:INN]
Diazoxide [USAN:INN:BAN]
Diazoxido
Diazoxido [INN-Spanish]
Diazoxidum
Diazoxidum [INN-Latin]
Dizoxide
EINECS 206-668-1
EU-0100404
Eudemine
HMS1361B09
HMS1568A16
HMS1791B09
HMS1922L22
HMS1989B09
HMS2051P20
HMS2089L04
HMS2093N12
HMS2095A16
HMS2234B23
HMS3261A10
Hyperstat
Hyperstat (TN)
Hypertonalum
I06-2041
IDI1_033777
KBio2_000027
KBio2_002595
KBio2_005163
KBio3_000053
KBio3_000054
KBio3_001510
KBioGR_000027
KBioGR_001776
KBioSS_000027
Lopac-D-9035
Lopac0_000404
LS-40410
MLS000028459
MLS001076071
MolPort-003-666-772
Mutabase
NCGC00015380-01
NCGC00015380-02
NCGC00015380-03
NCGC00015380-04
NCGC00015380-05
NCGC00015380-06
NCGC00015380-07
NCGC00015380-08
NCGC00015380-09
NCGC00015380-10
NCGC00015380-11
NCGC00015380-12
NCGC00015380-13
NCGC00024907-01
NCGC00024907-02
NCGC00024907-03
NCGC00024907-04
NCGC00024907-05
NCGC00024907-06
NCGC00024907-07
NCGC00024907-08
nchembio.150-comp49
nchembio.476-comp10
NSC 64198
NSC 76130
NSC-64198
NSC64198
NSC76130
Prestwick0_000087
Prestwick1_000087
Prestwick2_000087
Prestwick3_000087
Prestwick_163
Proglicem
Proglycem
SAM001246872
Sch 6783
Sch-6783
SMR000058392
SPBio_001953
SPECTRUM2300206
Spectrum3_000735
Spectrum4_001248
SRG 95213
SRG-95213
Tocris-0964
UNII-O5CB12L4FN
VU0239714-6
ZINC03872277
ATC-Codes:
Side-Effects:
Side-EffectFrequency
unconsciousness0
choking0
somnolence0
decreased libido0
paralysis0
hirsutism0
myocardial ischemia0
nocturia0
phlebitis0
palpitations0
hypotension0
vomiting0
diarrhea0
nausea0
anxiety0
anorexia0
apprehension0
euphoria0
headache0
leukopenia0
flushing0
shock0
malaise0
fever0
bradycardia0
cataract0
coma0
loss of consciousness0
hearing loss0
convulsions0
cough0
rash0
myocardial infarction0
blurred vision0
supraventricular tachycardia0
increased salivation0
arrhythmia0
weakness0
constipation0
back pain0
acute pancreatitis0
cellulitis0
lightheadedness0
hypersensitivity0
confusion0
sweating0
angina pectoris0
swelling0
postural hypotension0
numbness0
dry mouth0
dyspnea0
papilledema0
dizziness0
cerebral ischemia0
elevated blood pressure0
hyperglycemia0
pain0

Target

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Uniprot ID:ADRB1_HUMAN
Synonyms:
Beta-1 adrenergic receptor
Beta-1 adrenoceptor
Beta-1 adrenoreceptor
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
---0.084
---0.84
---6
---12
---100
---1000
---2200

References: