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Drug-Target Interaction

Drug

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PubChem ID:2995
Structure:
Synonyms:
(3-(10H,11H-Dibenzo[b,f]azepin-5-yl)propyl)methylamine
(3-(10H,11H-Dibenzo[b,f]azepin-5-yl)propyl)methylamine;
10, 11-Dihydro-N-methyl-5H-dibez[b,f]azepine-5-propanamine
10,11-Dihydro-5-(3-methylaminopropyl)-5H-dibenz(b,f)azepine
3-(10,11-DIHYDRO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N-METHYLPROPAN-1-AMINE
3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine
5-(gamma-Methylaminopropyl)iminodibenzyl
5-20-08-00096 (Beilstein Handbook Reference)
50-47-5
50-47-5 (FREE BASE)
58-28-6
58-28-6 (hydrochloride)
5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(methylamino)propyl)-
5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N-methyl-
5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N-methyl-
AB00053450
AC-15977
AC1L1EXQ
AIDS-110071
AIDS110071
AKOS001681456
BPBio1_000447
BRN 1432747
BSPBio_000405
BSPBio_002137
C06943
C18H22N2
CAS-58-28-6
CCG-118231
CCRIS 7091
CHEBI:47781
CHEMBL72
D07791
DB01151
DB07682
Demethylimipramine
Desimipramine
Desimpramine
Desipramin
Desipramina
Desipramina [INN-Spanish]
Desipramine
Desipramine (D4)
Desipramine (INN)
Desipramine Hcl
Desipramine hydrochloride
Desipramine [INN:BAN]
desipraminum
Desipraminum [INN-Latin]
Desmethylimipramine
Dezipramine
Dimethylimipramine
DivK1c_000190
DMI
DMI (pharmaceutical)
DMI 50475
DSM
EINECS 200-040-0
HSDB 3052
IDI1_000190
Imipramine, demethyl-
KBio1_000190
KBio2_000921
KBio2_003489
KBio2_006057
KBio3_001357
KBioGR_000928
KBioSS_000921
L001089
Lopac-D-3900
Lopac0_000358
LS-60421
Methylaminopropyliminodibenzyl
Monodemethylimipramine
N-(3-Methylaminopropyl)iminobibenzyl
NCGC00015340-01
NCGC00015340-02
NCGC00015340-03
NCGC00015340-04
NCGC00015340-05
NCGC00015340-06
NCGC00015340-07
NCGC00015340-08
NCGC00015340-09
NCGC00015340-10
NCGC00015340-11
NCGC00024375-04
NINDS_000190
Norimipramine
Norpramine
Pentofran
Pertofran
Pertofrane
Pertrofane
Prestwick0_000343
Prestwick1_000343
Prestwick2_000343
Prestwick3_000343
Sertofran
SPBio_000042
SPBio_002326
Spectrum2_000091
Spectrum3_000379
Spectrum4_000314
Spectrum5_000833
Spectrum_000441
ST052019
STK735144
STOCK2S-34822
UNII-TG537D343B
ZERO/006017
ATC-Codes:
Side-Effects:
Side-EffectFrequency
decreased libido0
psychosis0
distended bladder0
palpitations0
urinary retention0
mental depression0
breast enlargement0
nocturia0
adenitis0
anxiety0
vomiting0
petechiae0
arrhythmia0
tachycardia0
hypotension0
insomnia0
sweating0
agitation0
diarrhea0
tinnitus0
somnolence0
testicular swelling0
eosinophilia0
cardiac arrest0
shock0
abdominal cramps0
elevated liver function tests0
impotence0
swelling0
urinary frequency0
hallucinations0
malaise0
bradycardia0
flushing0
siadh0
nausea0
headache0
anorexia0
grand mal0
alopecia0
tremor0
delusions0
gynecomastia0
cerebrovascular accident0
purpura0
fever0
weakness0
blurred vision0
myocardial infarction0
congestive heart failure0
lightheadedness0
stomatitis0
increased salivation0
fatigue0
constipation0
edema0
rash0
coma0
galactorrhea0
seizures0
numbness0
paresthesia0
ventricular extrasystoles0
thrombocytopenia0
hepatitis0
bronchospasm0
urticaria0
weight gain0
ventricular tachycardia0
dry mouth0
dizziness0
paralytic ileus0
ventricular fibrillation0
agranulocytosis0
ataxia0
heart block0
confusion0
nodal tachycardia0
alkaline phosphatase increased0
pruritus0
hyperacusis0
hypertension0
peripheral neuropathy0
nightmares0
jaundice0

Target

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Uniprot ID:CP1A2_HUMAN
Synonyms:
CYPIA2
Cytochrome P450 1A2
P(3)450
P450 4
P450-P3
EC-Numbers:1.14.14.1
Organism:Homo sapiens
Human
PDB IDs:2HI4
Structure:
2HI4

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: