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Drug-Target Interaction

Drug

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PubChem ID:2955
Structure:
Synonyms:
"sulfona;diaminodiphenylsulfone;4-aminophenylsulfone"
(4-sulfanilylphenyl)amine
1,1'-Sulfonylbis(4-aminobenzene)
1,1'-Sulfonylbis[4-aminobenzene]
1,1'-Sulphonylbis(4-aminobenzene)
1358F
32960_FLUKA
4,4 inverted
4,4 inverted exclamation marka-Diaminodiphenyl sulfone
4,4' Diaminophenyl Sulfone
4,4'-Dapsone
4,4'-Diaminodiphenyl sulfone
4,4'-Diaminodiphenyl suphone
4,4'-Diaminodiphenylsulfone
4,4'-diaminophenyl sulfone
4,4'-Sulfonylbisaniline
4,4'-Sulfonylbisbenzamine
4,4'-Sulfonylbisbenzenamine
4,4'-Sulfonyldianiline
4,4'-Sulfonyldianiline (Dapsone)
4,4'-Sulphonylbisbenzamine
4,4'-Sulphonylbisbenzenamine
4,4'-Sulphonyldianiline
4,4-Diaminodifenylsulfon
4,4-Diaminodifenylsulfon [Czech]
4,4-Sulfonyldianiline
4-(4-aminophenyl)sulfonylaniline
4-13-00-01306 (Beilstein Handbook Reference)
4-Aminop henyl sulfone
4-Aminophenyl sulfone
4-Aminophenylsulfone
4-[(4-aminobenzene)sulfonyl]aniline
4-[(4-aminophenyl)sulfonyl]aniline
46158_FLUKA
46158_RIEDEL
80-08-0
A74807_ALDRICH
AB00051962
AB1004833
AC-10922
AC1L1EUH
AC1Q51WM
AC1Q51WN
Acedapsone
Aczone
Aczone (TN)
AG-H-21104
AI3-08087
AIDS-005738
AIDS005738
AKOS000119322
ALBB-005917
Ambap3158
Ambap80-08-0
Aniline, 4,4'-sulfonyldi-
Araldite HT
Araldite HT 976
Atrisone
Avlosulfon
Avlosulfone
Avlosulphone
Avsulfor
AZT + Dapsone cominbation
BBL002412
Benzenamine, 4,4'-sulfonylbis-
BIDD:GT0770
Bis(4-aminophenyl) sulfone
Bis(4-aminophenyl)sulfone
Bis(4-aminophenyl)sulphone
Bis(p-aminophenyl) sulfone
Bis(p-aminophenyl)sulphone
BPBio1_000143
BRD-K62363391-001-05-8
BRN 0788055
BSPBio_000129
BSPBio_002129
C07666
C12H12N2O2S
CAS-80-08-0
CBDivE_013582
CCG-40260
CCRIS 192
CHEBI:4325
CHEMBL1043
CPD000059064
Croysulfone
Croysulphone
D SS
D003622
D00592
D0089
DADPS
Dapsoderm-X
Dapson
Dapson-Fatol
Dapsona
Dapsona [INN-Spanish]
Dapsone
Dapsone (USP)
Dapsone [USAN:BAN]
Dapsonum
Dapsonum [INN-Latin]
DB00250
DDS
DDS (pharmaceutical)
Dds, Diaphenylsulfone
DDS, pharmaceutical
Di(4-aminophenyl) sulfone
Di(4-aminophenyl)sulfone
Di(4-aminophenyl)sulphone
Di(p-aminophenyl) sulfone
Di(p-aminophenyl)sulphone
Diamino-4,4'-diphenyl sulfone
Diamino-4,4'-diphenyl sulphone
Diamino-diphenyl sulphone
Diaminodifenilsulfona
Diaminodifenilsulfona [Spanish]
Diaminodiphenyl sulfone
Diaminodiphenylsulfone
Diaphenylsulfon
Diaphenylsulfone
Diaphenylsulfone (JAN)
Diaphenylsulphon
Diaphenylsulphone
Diphenasone
Diphone
Disulone
DivK1c_000573
DRG-0036
DSS
DSS (VAN)
Dubronax
Dubronaz
Dumitone
EINECS 201-248-4
Eporal
F 1358
Fatol Brand of Dapsone
Hardener HT 976
HMS1568G11
HMS1920C14
HMS2091K04
HMS2095G11
HMS2231G09
HMS3259C13
HMS501M15
HSDB 5073
HT 976
HY 976
I01-3640
ICI
IDI1_000573
IN-201
KBio1_000573
KBio2_001368
KBio2_003936
KBio2_006504
KBio3_001349
KBioGR_000900
KBioSS_001368
LS-1790
Metabolite C
Mex-America Brand of Dapsone
MLS000069409
MLS001055349
MLS001076146
N'-Diphenyl sulfondiamide
N, N'-Diphenyl Sulfondiamide
N,N'-Diphenyl sulfondiamide
NCGC00016322-01
NCGC00016322-02
NCGC00016322-03
NCGC00016322-04
NCGC00016322-05
NCGC00016322-06
NCGC00016322-07
NCGC00016322-08
NCGC00016322-09
NCGC00016322-10
NCGC00023946-03
NCGC00023946-04
NCGC00023946-05
NCGC00023946-06
NCI-C01718
NINDS_000573
Novophone
NSC 6091
NSC 6091D
NSC-6091
NSC6091
Oprea1_143052
Orsade Brand of Dapsone
P, P'-Sulfonyldianiline
p,p'-Diaminodiphenyl sulfone
p,p'-Sulfonyldianiline
p,p-Diaminodiphenyl sulphone
p,p-Sulfonylbisbenzamine
p,p-Sulfonylbisbenzenamine
p,p-Sulphonylbisbenzamine
p,p-Sulphonylbisbenzenamine
p,p-Sulphonyldianiline
p-Aminophenyl sulfone
Prestwick0_000035
Prestwick1_000035
Prestwick2_000035
Prestwick3_000035
Prestwick_152
Protogen
SAM002554879
SBB003168
Slphadione
SMR000059064
SPBio_001025
SPBio_002050
SPECTRUM1500222
Spectrum2_001133
Spectrum3_000375
Spectrum4_000310
Spectrum5_000825
Spectrum_000888
STK387118
Sulfadione
Sulfanona-mae
sulfon-mere
Sulfona
Sulfona-MAE
Sulfona;Diaminodiphenylsulfone;4-Aminophenylsulfone
Sulfone UCB
Sulfone, 4,4'-Diaminophenyl
Sulfone, diphenyl, 4,4'-diamino-
Sulfonyldianiline
Sulphadione
Sulphon-mere
Sulphonyldianiline
Sumicure S
Tarimyl
TL8005401
Udolac
UNII-8W5C518302
W R 448
WLN: ZR DSWR DZ
WR 448
ZINC00006310
ATC-Codes:
Side-Effects:
Side-EffectFrequency
erythema0.067999996
nasopharyngitis0.05
headache nos0.04
cough0.02
sinusitis nos0.02
pharyngitis0.02
pruritus0.01
influenza0.01
pyrexia0.01
suicide attempt0
vomiting0
pancreatitis0
abdominal pain0
swelling0

Target

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Uniprot ID:DHPS2_MYCLE
Synonyms:
DHPS 2
Dihydropteroate pyrophosphorylase 2
Dihydropteroate synthase 2
EC-Numbers:2.5.1.15
Organism:Mycobacterium leprae
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: