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Drug-Target Interaction

Drug

show drug details
PubChem ID:28417
Structure:
Synonyms:
(1R,3aS,3bR,10aR,10bS,12aS)-1-ethynyl-10a,12a-dimethyl-2,3,3a,3b,4,5,10,10
(1R,3aS,3bR,10aR,10bS,12aS)-1-ethynyl-10a,12a-dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta[7,8]phenanthro[3,2-d]isoxazol-1-ol
1-Ethynyl-10a,12a-dimethyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-1H-cyclopenta[7,8]phenanthro[3,2-d]isoxazol-1-ol
17-alpha-2,4-Pregnadien-20-yno(2,3-d)isoxazol-17-ol
17-alpha-Pregn-4-en-20-yno(2,3-d)isoxazol-17-ol
17-alpha-Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol
17.Alpha.-Pregna-2, {4-dien-20-yno[2,3-d]isoxazol-17-ol}
17230-88-5
17alpha-Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol
AIDS-128400
AIDS128400
anatrol
BPBio1_000100
BSPBio_000090
C22H27NO2
CCRIS 6747
CHEBI:4315
Chronogyn
Cyclomen
D00289
Danatrol
Danazol
Danazol (JAN/USP/INN)
Danazol [USAN:BAN:INN:JAN]
Danazole
Danazolum
Danazolum [INN-Latin]
Danocrine
Danocrine (TN)
Danogen
Danokrin
Danol
Danoval
Danzol
DB01406
EINECS 241-270-1
Ladogal
LS-118524
MLS001066617
MLS001306473
NCGC00179665-01
NSC 270916
NSC270916
Panacrine
Pregna-2, {4-dien-20-yno[2,3-d]isoxazol-17-ol,} (17.alpha.)-
Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol, (17alpha)-
Pregna-2,4-dien-20-yno(2,3-d)isoxazol-17-ol,(17alpha)-
Prestwick0_000105
Prestwick1_000105
Prestwick2_000105
Prestwick3_000105
Prestwick_150
SMR000058321
SPBio_002029
STOCK1N-23495
Win 17, 757
WIN 17,757
WIN 17757
Winobanin
ZINC03881958
[1,2]oxazolo[4',5':2,3]-17alpha-pregn-4-en-20-yn-17-ol
ATC-Codes:
Side-Effects:
Side-EffectFrequency
sleep disorder0
stevens - johnson syndrome0
spasm0
seborrhea0
purpura0
pseudotumor cerebri0
pruritus0
polycythemia0
pelvic pain0
paresthesia0
weakness0
pancreatitis0
nervousness0
sweating0
syncope0
thrombocytopenia0
acne0
photosensitivity0
sore throat0
joint swelling0
nipple discharge0
cataract0
emotional lability0
chills0
weight gain0
vomiting0
urticaria0
tremor0
tumor0
nausea0
fatigue0
eosinophilia0
edema0
dizziness0
convulsions0
constipation0
carpal tunnel syndrome0
back pain0
arthralgia0
anxiety0
amenorrhea0
alopecia0
fever0
flushing0
gastroenteritis0
nasal congestion0
muscle cramps0
metrorrhagia0
leukopenia0
leukocytosis0
jaundice0
hoarseness0
hirsutism0
hemorrhage0
hematuria0
headache0
gum hemorrhage0
adenomas0

Target

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Uniprot ID:SHBG_HUMAN
Synonyms:
ABP
SBP
Sex hormone-binding globulin
Sex steroid-binding protein
SHBG
TeBG
Testis-specific androgen-binding protein
Testosterone-estradiol-binding globulin
Testosterone-estrogen-binding globulin
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:1D2S 1F5F 1KDK 1KDM 1LHN 1LHO 1LHU 1LHV 1LHW
Structure:
1LHW

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----
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References: