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Drug-Target Interaction

Drug

show drug details
PubChem ID:2801
Structure:
Synonyms:
10,11-dihydro-3-chloro-5-(3-(dimethylamino)propyl)-5H-dibenz(b,f)azepine
17321-77-6
3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine
3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1
3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine
3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE
3-(9-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine
3-chloro-10,11-dihydro-N,N-dimethyl-5H-Dibenz(b,f)azepine-5-propanamine
3-Chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine
3-Chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-5H-dibenz[b,f]azepine
3-Chloroimipramine
303-49-1
303-49-1 (FREE BASE)
5-20-08-00103 (Beilstein Handbook Reference)
5H-Dibenz(b,f)azepine, 10,11-dihydro-3-chloro-5-(3-(dimethylamino)propyl)-
5H-Dibenz(b,f)azepine, 3-chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro-
5H-Dibenz(b,f)azepine, 3-chloro-5-(3-(dimethylamino)propyl)-10,11-dihydro- (8CI)
5H-Dibenz(b,f)azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-
5H-Dibenz[b,f]azepine, 10,11-dihydro-3-chloro-5-[3-(dimethylamino)propyl]-
5H-Dibenz[b,f]azepine, 3-chloro-5-[3-(dimethylamino)propyl]-10,11-dihydro-
5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N,N-dimethyl-
83162-38-3
AB00053695
AIDS-059769
AIDS059769
Anafranil
Anafranil (free base)
Anafranil (TN)
Anafranil base
Biomol-NT_000151
BPBio1_000130
BPBio1_000661
BRN 1323477
BSPBio_000118
BSPBio_003294
C06918
C14H12ClN.C6H15N
CAS-17321-77-6
CHEBI:47780
Chlomipramine
Chlorimipramine
Clomipramina [INN-Spanish]
Clomipramine
Clomipramine (INN)
Clomipramine HCL
Clomipramine hydrochloride
Clomipramine [INN:BAN]
Clomipraminum [INN-Latin]
D07727
DB01242
DivK1c_000797
EINECS 206-144-2
G 34586
G-34586
Hydiphen
IDI1_000797
KBio1_000797
KBio2_000924
KBio2_003492
KBio2_006060
KBio3_002514
KBioGR_000759
KBioSS_000924
KS-1044
Lopac-C-7291
Lopac0_000307
LS-60386
Monochlorimipramine
NCGC00015264-01
NCGC00015264-02
NCGC00015264-03
NCGC00024355-02
NCGC00024355-04
NCGC00024355-05
NINDS_000797
NSC 169865
NSC169865
Oprea1_312582
PDSP1_000241
PDSP2_000240
Prestwick0_000269
Prestwick1_000269
Prestwick2_000269
Prestwick3_000269
SPBio_001778
SPBio_002337
Spectrum2_001729
Spectrum3_001707
Spectrum4_000350
Spectrum5_001235
Spectrum_000444
Tocris-0457
WLN: T C676 BN & T & J B3N1 & 1 EG
ATC-Codes:
Side-Effects:
Side-EffectFrequency
vertigo1.0
epididymitis0.01
hyperacusis0.01
psychosis0.01
psoriasis0.01
pruritus0.01
polyuria0.01
pneumonia0.01
gastritis0.01
gastroesophageal reflux0.01
diabetes mellitus0.01
scleritis0.01
suicide attempt0.01
diplopia0.01
gastric ulcer0.01
duodenitis0.01
dyskinesia0.01
somnambulism0.01
earache0.01
eczema0.01
endometriosis0.01
peptic ulcer0.01
gingivitis0.01
hemorrhoids0.01
hepatitis0.01
hypercholesterolemia0.01
hyperglycemia0.01
leg cramps0.01
renal calculus0.01
hypokalemia0.01
hypothyroidism0.01
arthrosis0.01
blood in stool0.01
hematuria0.01
glossitis0.01
pain0.01
ovarian cyst0.01
gout0.01
irritable bowel syndrome0.01
nocturia0.01
hallucinations0.01
cardiac arrest0.01
neuralgia0.01
infection0.01
bradycardia0.01
abnormal gait0.01
phobic disorder0.01
colitis0.01
photophobia0.01
abnormal eeg0.01
renal pain0.01
cellulitis0.01
abnormal ecg0.01
bronchitis0.01
eye pain0.01
sensory disturbance0.01
malaise0.01
lymphadenopathy0.01
rectal hemorrhage0.01
ataxia0.01
photosensitivity0.01
arrhythmia0.01
encephalopathy0.01
paranoia0.01
dehydration0.01
delirium0.01
coma0.01
ulceration0.01
alopecia0.01
cyst0.01
urinary incontinence0.01
uterine hemorrhage0.01
tooth caries0.01
dysphonia0.01
hyperuricemia0.01
deafness0.01
convulsions0.01
vaginal hemorrhage0.01
edema0.0055
rash0.0046
neuropathy0.0010
ischemia0.0010
lupus0.0010
exostosis0.0010
keratitis0.0010
renal cyst0.0010
lymphoma0.0010
nystagmus0.0010
premature ejaculation0.0010
chloasma0.0010
myopathy0.0010
myocardial infarction0.0010
hypoventilation0.0010
choreoathetosis0.0010
ventricular tachycardia0.0010
visual field defect0.0010
seborrhea0.0010
skin ulceration0.0010
spasm0.0010
gastric dilatation0.0010
strabismus0.0010
retinal disorder0.0010
pyuria0.0010
myositis0.0010
night blindness0.0010
nerve paralysis0.0010
paralytic ileus0.0010
torticollis0.0010
myocardial ischemia0.0010
polyarteritis nodosa0.0010
pyelonephritis0.0010
thrombophlebitis0.0010
albuminuria0.0010
gynecomastia0.0010
goiter0.0010
glycosuria0.0010
glaucoma0.0010
folliculitis0.0010
exophthalmos0.0010
enteritis0.0010
endometrial hyperplasia0.0010
aphasia0.0010
cervical dysplasia0.0010
cerebral hemorrhage0.0010
bundle branch block0.0010
blepharitis0.0010
atrial flutter0.0010
apraxia0.0010
aneurysm0.0010
heart block0.0010
hemorrhage0.0010
hyperesthesia0.0010
hypertrichosis0.0010
hyperthyroidism0.0010
hiccup0.0010
salivary gland enlargement0.0010
hemoptysis0.0010
hemiparesis0.0010
cardiac failure0.0010
gingival bleeding0.0010
migraine0
vestibular disorders0
breast enlargement0
bruxism0
bronchospasm0
dry skin0
constipation0
blepharospasm0
chest pain0
emotional lability0
apathy0
vomiting0
weight gain0
weight loss0
dry mouth0
urinary retention0
conjunctivitis0
confusion0
chills0
abnormal vision0
agitation0
stupor0
myalgia0
impotence0
manic0
anemia0
urinary frequency0
increased sweating0
acne0
als0
sleep disorder0
insomnia0
amenorrhea0
anisocoria0
anorexia0
thinking abnormal0
hypnagogic hallucinations0
memory impairment0
back pain0
postural hypotension0
asthenia0
arthralgia0
illusion0
dermatitis0
anxiety0
muscle weakness0
nausea0
fever0
fatigue0
psychosomatic disorder0
purpura0
euphoria0
esophagitis0
eructation0
epistaxis0
rhinitis0
breast pain0
laryngitis0
flatulence0
flushing0
headache0
halitosis0
otitis media0
palpitations0
menstrual disorder0
weakness0
paresthesia0
irritability0
nervousness0
pharyngitis0
abdominal pain0
seizures0
tinnitus0
tooth disorder0
depersonalization0
tremor0
delusions0
dysphagia0
urinary tract infection0
urticaria0
cystitis0
vaginitis0
hypersensitivity0
tachycardia0
syncope0
sinusitis0
dysuria0
dyspnea0
dyspepsia0
dysmenorrhea0
somnolence0
ulcerative stomatitis0
dizziness0
diarrhea0
sweating0
cough0

Target

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Uniprot ID:CP2CJ_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC17
CYPIIC19
Cytochrome P450 2C19
Mephenytoin 4-hydroxylase
P450-11A
P450-254C
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: