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Drug-Target Interaction

Drug

show drug details
PubChem ID:2678
Structure:
Synonyms:
(2-(4-((4-Chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)acetic acid
(2-{4-[(4-Chloro-phenyl)-phenyl-methyl]-piperazin-1-yl}-ethoxy)-acetic
(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid
83881-51-0
83881-52-1
Acetic acid, (2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-
BPBio1_000469
BSPBio_000425
BSPBio_002302
C07778
C21H25ClN2O3
Cetiderm
Cetiderm (TN)
Cetirizin
Cetirizina
Cetirizina [Spanish]
Cetirizine
Cetirizine (INN)
Cetirizine [INN:BAN]
Cetirizinum
Cetirizinum [Latin]
Cetrizine Hcl
Cetryn
CHEBI:3561
D07662
DB00341
Hitrizin Film Tablet
LS-11409
NCGC00167781-01
NCGC00167781-02
NCGC00167781-03
nchembio714-comp3
P-071
Prestwick0_000503
Prestwick1_000503
Prestwick2_000503
Prestwick3_000503
Setir
SMR000145214
SPBio_002346
ST024755
TimTec1_002075
Virlix
Ziptek
Zirtek
Zyrlex
Zyrtec
[(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethyl)oxy]acetic acid
ATC-Codes:
Side-Effects:
Side-EffectFrequency
headache0.1245
nasopharyngitis0.0483828
abdominal pain0.042249996
pyrexia0.0411523
pharyngitis0.038387105
coughing0.03652481
somnolence0.029266968
epistaxis0.028040668
fatigue0.0274336
dry mouth0.02640135
bronchospasm0.024999999
diarrhea0.021999998
nausea0.021769227
vomiting0.020500002
agitation0.0010
palpitations0.0010
pruritus0.0010
thrombocytopenia0.0010
convulsion0.0010
syncope0.0010
urticaria0.0010
still birth0.0010
myalgia0.0010
dyspnea0.0010
anaphylaxis0.0010
hemolytic anemia0.0010
angioneurotic edema0.0010
convulsions0.0010
drug eruption0.0010
dyskinesia0.0010
rash0.0010
glomerulonephritis0.0010
hallucinations0.0010
hepatitis0.0010
hypersensitivity0.0010
hypotension0.0010
thyroid disorder0
peripheral edema0
dysmenorrhea0
dyspepsia0
dermatitis0
asthma0
anorexia0
migraine0
polyuria0
vaginitis0
fungal infection0
infection0
ptosis0
tachycardia0
glaucoma0
constipation0
paresthesia0
deafness0
hematuria0
heart failure0
ulcerative stomatitis0
stomatitis0
dry skin0
nervousness0
ulcer0
eye pain0
urinary frequency0
eructation0
rhinitis0
arthralgia0
upper respiratory tract infection0
dysphonia0
menstrual disorder0
arthritis0
melena0
hyperkeratosis0
leg cramps0
thinking abnormal0
depersonalization0
emotional lability0
irritability0
breast pain0
nasal polyps0
amnesia0
tremor0
hypertrichosis0
hemorrhage0
dehydration0
chest pain0
weight gain0
abnormal vision0
increased sweating0
insomnia0
hot flashes0
anxiety0
euphoria0
allergic reaction0
gastritis0
arrhythmia0
sleep disorder0
urinary retention0
visual field defect0
pain0
decreased libido0
herpes simplex0
metrorrhagia0
eczema0
alopecia0
photosensitivity0
menorrhagia0
jaundice0
furunculosis0
lymphadenopathy0
ear pain0
back pain0
rectal hemorrhage0
increased salivation0
acne0
confusion0
urinary tract infection0
muscle weakness0
blindness0
hypertension0
myelitis0
flushing0
conjunctivitis0
tinnitus0
diabetes mellitus0
bronchitis0
concentration impaired0
skin nodule0
dysuria0
paralysis0
eye abnormality0
arthrosis0
viral infection0
urinary incontinence0
cystitis0
vertigo0
asthenia0
pneumonia0
sinusitis0
seborrhea0
purpura0
flatulence0
hyperesthesia0
tooth caries0
hemorrhoids0
edema0
nightmares0
dizziness0
ataxia0
malaise0

Target

show target details
Uniprot ID:HRH4_HUMAN
Synonyms:
AXOR35
G-protein coupled receptor 105
GPRv53
HH4R
Histamine H4 receptor
Pfi-013
SP9144
EC-Numbers:-
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
>10000---

References: