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Drug-Target Interaction

Drug

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PubChem ID:2585
Structure:
Synonyms:
(+)-1-(carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+/-)-1-(Carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol
1-(9H-carbazol-4-yloxy)-3-[(2-{[2-(methyloxy)phenyl]oxy}ethyl)amino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol
107741-96-8
2-Propanol, 1-(9H-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)-
2-Propanol, 1-(9H-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)-,
2-propanol, 1-(9h-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)-, (+)-
2-Propanol, 1-(9H-carbazol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)-, (+-)-
72956-09-3
Artist
Artist (TN)
Atlana Pharma brand of carvedilol
BM 14190
BM-14190
C043211
C06875
C24H26N2O4
Carvedilol
Carvedilol (JAN/USAN/INN)
Carvedilol [USAN:BAN:INN:JAN]
Carvedilol [USAN:INN:BAN:JAN]
carvedilol, (+-)-isomer
carvedilol, (R)-isomer
carvedilol, (S)-isomer
carvedilol, 14C-labeled
Carvedilolum
Carvedilolum [Latin]
CHEBI:3441
Coreg
Coreg (TN)
Coreg CR
Coropres
Coropress
CPD000449280
D00255
DB01136
Dibloc
Dilatrend
Dimitone
DQ 2466
DQ-2466
Eucardic
GlaxoSmithKline brand of carvedilol
HSDB 7044
KBio2_002145
KBio2_004713
KBio2_007281
KBio3_002323
KBioGR_001252
KBioSS_002145
Kredex
KS-1037
Lakeside brand of carvedilol
LS-121875
MLS000758299
MLS000759508
MLS001424092
NCGC00167832-01
NCGC00167832-02
Querto
Roche brand of carvedilol
SAM001246736
SAM001247021
SK&F-105517
SKF 105517
SMR000449280
SPBio_001885
Spectrum2_001673
Spectrum3_001182
Spectrum4_000636
Spectrum5_001436
Spectrum_001665
TL8005080
ATC-Codes:
Side-Effects:
Side-EffectFrequency
urticaria0.0010
interstitial pneumonitis0.0010
stevens - johnson syndrome0.0010
hypersensitivity0.0010
angioedema0.0010
aplastic anemia0.0010
anaphylactic reaction0.0010
urinary incontinence0.0010
toxic epidermal necrolysis0.0010
erythema multiforme0.0010
upper respiratory tract infection0
rhinitis0
sinusitis0
cerebrovascular accident0
sweating0
syncope0
tachycardia0
thrombocytopenia0
urinary tract infection0
erythema0
tinnitus0
renal failure0
purpura0
nausea0
nervousness0
neuralgia0
nightmares0
pain0
palpitations0
pancytopenia0
weakness0
paresthesia0
periodontitis0
pharyngitis0
pneumonia0
pruritus0
pulmonary edema0
nasopharyngitis0
vascular disorders0
sinus congestion0
malaise0
myalgia0
thinking abnormal0
blurred vision0
photosensitivity0
bradycardia0
urinary frequency0
increased sweating0
hyperuricemia0
sleep disorder0
cardiomyopathy0
insomnia0
hearing loss0
sgot increased0
alkaline phosphatase increased0
chest pain substernal0
ventricular tachycardia0
vertigo0
viral infection0
abnormal vision0
vomiting0
weight gain0
weight loss0
dry mouth0
peripheral vascular disorder0
sinus bradycardia0
emotional lability0
peripheral edema0
migraine0
myocardial ischemia0
renal insufficiency0
nasal congestion0
abdominal pain0
bronchitis0
bundle branch block0
cerebrovascular disorder0
chest pain0
confusion0
convulsions0
cough0
decreased libido0
dehydration0
dermatitis0
exfoliative dermatitis0
diabetes mellitus0
diarrhea0
dizziness0
bronchospasm0
clotting0
albuminuria0
respiratory alkalosis0
alopecia0
amnesia0
anemia0
angina pectoris0
anorexia0
arthralgia0
arthritis0
asthenia0
asthma0
atrial fibrillation0
av block0
back pain0
somnolence0
dyspepsia0
dyspnea0
hypoglycemia0
hypokalemia0
hyponatremia0
hypotension0
postural hypotension0
impotence0
infection0
influenza0
ischemia0
acute renal failure0
leg cramps0
leukopenia0
lung disorder0
melena0
hypertriglyceridemia0
hyperkalemia0
edema0
rash0
fatigue0
fever0
flatulence0
gastrointestinal hemorrhage0
glycosuria0
gout0
headache0
hematuria0
hemorrhage0
bilirubinemia0
hypercholesterolemia0
hyperglycemia0
muscle cramps0

Target

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Uniprot ID:CP2E1_HUMAN
Synonyms:
4-nitrophenol 2-hydroxylase
CYPIIE1
Cytochrome P450 2E1
P450-J
EC-Numbers:1.14.13.-
1.14.13.n7
Organism:Homo sapiens
Human
PDB IDs:3E4E 3E6I
Structure:
3E6I

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: