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Drug-Target Interaction

Drug

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PubChem ID:24466
Structure:
Synonyms:
197U50
2,4-Diamino-5-(3',4'-dichlorophenyl)-6-methyl pyrimidine
2,4-Diamino-5-(3,4-dichlorophenyl)-6-methylpyrimidine
2,4-Pyrimidinediamine, 5-(3,4-dichlorophenyl)-6-methyl-
2aov
5-(3,4-Dichlorophenyl)-6-methyl-2,4-pyrimidinediamine
5-(3,4-DICHLOROPHENYL)-6-METHYLPYRIMIDINE-2,4-DIAMINE
5-(3,4-Dichlorphenyl)-6-methyl-2,4-pyrimidindiamin
5-25-12-00253 (Beilstein Handbook Reference)
7761-45-7
AC1L2NGD
AC1Q2OZ6
AI3-26402
AIDS-006915
AIDS006915
BRN 0223622
BW 197 U
BW 1970
BW 197U
BW 50,197
BW 50-197
BW 50197
BW-197U
BW50197
C11H10Cl2N4
C2M
CCG-35473
CHEBI:166251
CHEMBL264373
CPD-10891
D00309
DB04655
DDMP
LS-135022
Methodichlorophen
Metoprine
Metoprine (USAN)
Metoprine [USAN]
METOPRINE, METHODICHLOROPHEN
MLS002701892
NCI60_041610
NCIMech_000234
Neuro_000005
NSC 19494
NSC 7364
NSC-19494
NSC19494
NSC7364
Pyrimidine, 2,4-diamino-5-(3,4-dichlorophenyl)-6-methyl-
SK 5265
SMR001565478
TCMDC-123931
U 197
U-197
WLN: T6N CNJ BZ DZ ER CG DG& F1

Target

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Uniprot ID:HNMT_HUMAN
Synonyms:
Histamine N-methyltransferase
HMT
EC-Numbers:2.1.1.8
Organism:Homo sapiens
Human
PDB IDs:1ICZ 1JQD 1JQE 2AOT 2AOU 2AOV 2AOW 2AOX
Structure:
2AOX

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----

References: