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Drug-Target Interaction

Drug

show drug details
PubChem ID:24360
Structure:
Synonyms:
"4-ethyl-4-hydroxy-1h-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)dione"
()-camptothecin
()-camptothecine
(+)-Camptothecin
(+)-Camptothecine
(4S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14
(4S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
(s)-()-camptothecin
(S)-(+)-Camptothecin
(S)-4-ethyl-4-hydroxy-1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione
(S)-Camptothecin
1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-, (4S)-
1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-, (S)-
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-, (S)-
20(S)-Camptothecin
20(S)-Camptothecine
21,22-Secocamptothecin-21-oic acid lactone
25387-67-1 (SODIUM SALT)
4(S)-Ethyl-4-hydroxy-1H-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14 (4H,12H)-dione
4-ethyl-4-hydroxy-1,12-dihydro-4h-2-oxa-6,12a-diaza- Dibenzo[b,h]fluorene-3,13-dione
4-ETHYL-4-HYDROXY-1,12-DIHYDRO-4H-2-OXA-6,12A-DIAZA-DIBENZO[B,H]FLUORENE-3,13-DIONE
4-Ethyl-4-hydroxy-1H-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
4-Ethyl-4-hydroxy-1H-pyrano-[3[,4[:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
4-Ethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione
7689-03-4
AI3-62475
AIDS-001995
AIDS001995
BB_NC-0996
Bio1_000400
Bio1_000889
Bio1_001378
BPBio1_000175
BRN 0631069
BSPBio_000159
BSPBio_002586
C01897
C9911_SIGMA
Camptothecin
Camptothecin derivative
Camptothecin, Camptotheca acuminata
Camptothecine
Camptothecine (8CI)
Camptothecine (S,+)
CAS-2114454
CCRIS 8162
CHEBI:27656
CPT
d-Camptothecin
DB04690
DivK1c_000826
DivK1c_006808
EHD
EU-0100341
IDI1_000826
KBio1_000826
KBio1_001752
KBio2_000779
KBio2_003347
KBio2_005915
KBio3_002086
KBioGR_001036
KBioSS_000779
KBioSS_002283
Lopac-C-9911
Lopac0_000341
MLS000766223
NCGC00015290-01
NCGC00016994-01
NCGC00024997-01
NCGC00024997-02
NCGC00024997-03
NCGC00024997-04
NCGC00024997-05
NCGC00024997-06
NCGC00178592-01
NCGC00178592-02
NCI60_042105
NINDS_000826
NSC 100880
NSC 94600
NSC94600
Prestwick0_000200
Prestwick1_000200
Prestwick2_000200
Prestwick3_000200
Prestwick_102
SDCCGMLS-0066688.P001
SMR000445686
SPBio_000746
SPBio_002080
SpecPlus_000712
SPECTRUM1502232
Spectrum2_000903
Spectrum3_001203
Spectrum4_000738
Spectrum5_001126
Spectrum_000299
Tocris-1100
ZINC00105309

Target

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Uniprot ID:RNAS1_BOVIN
Synonyms:
Ribonuclease pancreatic
RNase 1
RNase A
EC-Numbers:3.1.27.5
Organism:Bos taurus
Bovine
PDB IDs:1A2W 1A5P 1A5Q 1AFK 1AFL 1AFU 1AQP 1B6V 1BEL 1BZQ 1C0B 1C0C 1C8W 1C9V 1C9X 1CJQ 1CJR 1D5D 1D5E 1D5H 1DFJ 1DY5 1EIC 1EID 1EIE 1EOS 1EOW 1F0V 1FEV 1FS3 1GV7 1IZP 1IZQ 1IZR 1J7Z 1J80 1J81 1J82 1JN4 1JS0 1JVT 1JVU 1JVV 1KF2 1KF3 1KF4 1KF5 1KF7 1KF8 1KH8 1LSQ 1O0F 1O0H 1O0M 1O0N 1O0O 1QHC 1RAR 1RAS 1RAT 1RBB 1RBC 1RBD 1RBE 1RBF 1RBG 1RBH 1RBI 1RBJ 1RBN 1RBW 1RBX 1RCA 1RCN 1RHA 1RHB 1RNC 1RND 1RNM 1RNN 1RNO 1RNQ 1RNU 1RNV 1RNW 1RNX 1RNY 1RNZ 1ROB 1RPF 1RPG 1RPH 1RSM 1RTA 1RTB 1RUV 1SRN 1SSA 1SSB 1SSC 1U1B 1UN5 1W4O 1W4P 1W4Q 1WBU 1XPS 1XPT 1YMN 1YMR 1YMW 1Z3L 1Z3M 1Z3P 1Z6D 1Z6S 2AAS 2APQ 2APU 2BLP 2BLZ 2E33 2E3W 2G4W 2G4X 2G8Q 2G8R 2NUI 2OP2 2OQF 2P42 2P43 2P44 2P45 2P46 2P47 2P48 2P49 2P4A 2QCA 2RAT 2RLN 2RNS 2W5G 2W5I 2W5K 2W5L 2W5M 3A1R 3D6O 3D6P 3D6Q 3D7B 3D8Y 3D8Z 3DH5 3DH6 3DI7 3DI8 3DI9 3DIB 3DIC 3DXG 3DXH 3EUX 3EUY 3EUZ 3EV0 3EV1 3EV2 3EV3 3EV4 3EV5 3EV6 3FKZ 3FL0 3FL1 3FL3 3I7W 3I7X 3I7Y 3RAT 3RN3 3RSD 3RSK 3RSP 3SRN 4RAT 4RSD 4RSK 4SRN 5RAT 5RSA 6RAT 6RSA 7RAT 7RSA 8RAT 8RSA 9RAT 9RSA
Structure:
9RSA

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
-->300000-

References: