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Drug-Target Interaction

Drug

show drug details
PubChem ID:241
Structure:
Synonyms:
(6)Annulene
1120-89-4
121448-83-7
12197-22-7
12540_FLUKA
12553_FLUKA
12553_SIAL
154628_SIAL
174973-66-1
1hyz
1l83
1swi
220l
223l
26181-88-4
270709_ALDRICH
270709_SIAL
27271-55-2
2z9g
300019X
311855_SIGMA
319953_SIAL
32212_RIEDEL
32212_SIAL
322644_SIGMA
401765_ALDRICH
401765_SIAL
48503_SUPELCO
50813-73-5
50922-30-0
54682-86-9
54847-97-1
61789-95-5
676985_ALDRICH
676985_SIAL
68956-52-5
71-43-2
8002-05-9
8030-30-6
8030-31-7
8031-06-9
8032-32-4
8052-41-3
8052-42-4
:benzene
AC1L18SP
AG-G-79769
AI3-00808
Amsco H-J
Amsco H-SB
Aromatic alkane
Aromatic solvent
ASPHALT
Asphalt (Bitumen)fume as benzene-soluble aerosol
Asphalt (cut)
Asphalt (cutback)
Asphalt (petroleum)
Asphalt cements
Asphalt fumes
Asphalt [Bitumens]
Asphalt, at or above its flashpoint [NA1999] [Flammable liquid]
Asphalt, liquid medium-curing
Asphalt, liquid rapid-curing
Asphalt, liquid slow-curing
Asphaltic bitumen
Asphaltum
B0020
BASE oil
Benzeen
Benzeen [Dutch]
Benzen
Benzen [Polish]
BENZENE
Benzene (including benzene from gasoline)
Benzene + aniline combo
Benzene [UN1114] [Flammable liquid]
Benzene [UN1114] [Flammable liquid]
BENZENE, ACS
Benzene, labeled with carbon-14
Benzene, labeled with carbon-14 and tritium
Benzene, pure
Benzene-U-14C
Benzene-UL-14C
Benzin
Benzin (Obs.)
Benzin B70
Benzine
Benzine (light petroleum distillate)
Benzine (Obs.)
benzol
Benzol 90
Benzol diluent
benzole
Benzolene
Benzoline
Benzolo
Benzolo [Italian]
Benzyna DO lakierow C [Polish]
Bicarburet of hydrogen
Bitumen
Bitumens, asphalt
Bituminous materials, asphalt
BNZ
BP 2
BP 2 (solvent)
C01407
c0142
Canadol
Carbon oil
Caswell No. 062
Caswell No. 077
Caswell No. 106
Caswell No. 632A
Caswell No. 802
CCRIS 70
CHEBI:16716
CHEMBL277500
Coal naphtha
Coal oil [Oil, misc.]
Coal tar
Crankcase Oil, Used
Crankcase oil, used mineral-based
Crude oil
Crude oil [Oil, misc.]
Crude oil, petroleum
Crude oils
Crude petroleum
Cyclohexatriene
D001554
DEUTERO BENZENE
EINECS 200-753-7
EINECS 232-298-5
EINECS 232-443-2
EINECS 232-453-7
EINECS 232-489-3
EINECS 232-490-9
EPA Pesticide Chemical Code 008801
EPA Pesticide Chemical Code 022001
EPA Pesticide Chemical Code 022002
EPA Pesticide Chemical Code 063503
EPA Pesticide Chemical Code 063504
Fenzen
Fenzen [Czech]
FT-0080146
ghl.PD_Mitscher_leg0.503
Herbitox
HI-Flash naphtha
Hi-flash naphthayethylen
HSDB 2892
HSDB 35
HSDB 5075
HSDB 7171
HSDB 7177
Hydrocarbons, C4-8
Hydrotreated naphtha
Isoparaffinic hydrocarbons
Judean pitch
Light ligroin
LIGROIN
Ligroine
LS-1605
Mineral naphtha
Mineral oils, highly-refined oils [Mineral oils]
Mineral pitch
Mineral rubber (VAN)
Mineral spirits
Mineral spirits No. 10
Mineral thinner
Mineral turpentine
MolPort-000-871-944
Motor benzol
NA1999
Naphtha
Naphtha 49 degree be-coal tar type
Naphtha VM & P
Naphtha VM & P, 50 degree flash
Naphtha VM & P, high flash
Naphtha VM & P, regular
Naphtha, hydrotreated
Naphtha, ligroine
Naphtha, petroleum
Naphtha, solvent
Naphtha, stoddard solvent
Naphtha, varnish makers' and painters'
NCGC00090744-01
NCGC00090744-02
NCGC00163890-01
NCGC00163890-02
NCI-C55276
Nitration benzene
NSC 67315
NSC67315
Oil, crude
Organic slvents, Stoddard solvent
Painters' naphtha
Paraffinic oil
Petroleum
Petroleum asphalt
Petroleum benzin
Petroleum bitumen
Petroleum crude
Petroleum crude oil [UN1267] [Flammable liquid]
PETROLEUM DISTILLATE
Petroleum distillates
Petroleum distillates (naphtha)
Petroleum distillates Naphtha, Rubber Solvent
Petroleum distillates, n.o.s. or petroleum products, n.o.s. [UN1268] [Flammable liquid]
PETROLEUM ETHER
Petroleum naphtha
Petroleum pitch
Petroleum refining residues, asphalts
Petroleum roofing tar
Petroleum [Waxes]
Petroleum, light
Petroleum-derived naphtha
Phene
Phenyl hydride
PL9
Polystream
Pyrobenzol
Pyrobenzole
Q0038
RCRA waste no. U109
RCRA waste number U019
Refined solvent naphtha
RNG
Road asphalt
Road tar
Rock oil
Rubber solvent
Rubber solvent (Naphtha)
S0631
Seneca oil
Skelly-solve H
Skelly-solve R
Skelly-solve S
Skelly-solve S-66
Skellysolve F
Skellysolve G
Solvent naphtha
Solvents, naphthas
ST5214351
STODDARD SOLVENT
Super VMP
T5329368
TRANSGENIC MODEL EVALUATION II (BENZENE)
Trinidad pitch
UN 1114
UN1114
UN1267
UN1268
UNII-J64922108F
Unleaded gasoline
Used Mineral-based Crankcase Oil
V.M. and P. naphtha
Varnish makers' and painters naphtha
Varnish makers' naphtha
Varnish makers' naphtha and painters' naphtha
Varnish marker's naphtha
Varsol
Virol
VM & P Naphtha
VM and P Naphtha
White spirit
White spirits
WLN: RH
ZC3850000
[6]Annulene

Target

show target details
Uniprot ID:PPOB_SOLTU
Synonyms:
Catechol oxidase B, chloroplastic
Polyphenol oxidase
PPO
EC-Numbers:1.10.3.1
Organism:Potato
Solanum tuberosum
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
----

References:

1435072
Pyridine and other coal tar constituents as inhibitors of potato polyphenol oxidase: a non-animal model for neurochemical studies.. H M Henderson; N A Eskin; C Pinsky; R Bose; A M Ashique (1992) Life sciences display abstract
Potato polyphenol oxidase activity was strongly and noncompetitively inhibited by the "Perov mixture" of coal tar components and by pyridine alone, while phenol competitively inhibited the enzyme. These two inhibitors are structural components of the parkinsonogenic neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). By extension, dopamine and neuromelanin synthesis in the brain may be influenced by the inhibitory effects of such compounds upon the copper-dependent steps of tyrosine metabolism. The non-animal model used in this study may represent an alternative to the use of animal tissues in neurodegenerative disease research.