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Drug-Target Interaction

Drug

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PubChem ID:2375
Structure:
Synonyms:
(+-)-4'-Cyano-alpha,alpha,alpha-trifluoro-3-((p-fluorophenyl)sulfonyl)-2-methyl-m-lactotoluidide
4'-cyano-3-(4-fluorophenylsulfonyl)-2-hydroxy-2-methyl-3'-(trifluoromethyl)propionanilide
90357-06-5
Astra brand of bicalutamide
AstraZeneca brand of bicalutamide
Bicalutamide
Bicalutamide (JAN/USP/INN)
Bicalutamide [USAN:INN:BAN]
BRN 5364666
C053541
C08160
C18H14F4N2O4S
Casodex
Casodex (TN)
Casodex, Cosudex, Calutide, Kalumid, Bicalutamide
Cosudex
CPD000466329
D00961
ICI 176334
ICI-176334
LS-119125
MLS000759437
MLS001424047
NCGC00167977-01
NSC722665
Propanamide,
Propanamide, N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)sulfonyl)-2-hydroxy-2-methyl-, (+-)-
Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl-,
Raffolutil
SAM001246612
SMR000466329
TL8005814
Zeneca brand of bicalutamide
ATC-Codes:
Side-Effects:
Side-EffectFrequency
angioneurotic edema0.0010
hypersensitivity0.0010
pulmonary fibrosis0.0010
urticaria0.0010
interstitial pneumonitis0.0010
interstitial lung disease0.0010
liver function tests abnormal0
hydronephrosis0
gynecomastia0
cataract0
cardiac arrest0
urinary frequency0
sweating0
pelvic pain0
peripheral edema0
dysphagia0
ecchymosis0
breast disorders0
carcinoma0
somnolence0
mediastinal disorders0
influenza0
hirsutism0
gout0
weight gain0
rash0
constipation0
iron deficiency anemia0
paresthesia0
hematuria0
heart failure0
congestive heart failure0
dry skin0
nervousness0
hernia0
sgot increased0
cerebral ischemia0
infection0
diarrhea0
rhinitis0
periodontal abscess0
sepsis0
vomiting0
anxiety0
breast pain0
balanitis0
cyst0
deep thrombophlebitis0
neuropathy0
myalgia0
arthritis0
eosinophilia0
melena0
headache0
insomnia0
neck rigidity0
constitutional symptoms0
neck pain0
epistaxis0
thrombocytopenia0
hemorrhage0
neutropenia0
laboratory test abnormal0
dehydration0
hypochromic anemia0
dyspepsia0
abdominal pain0
dyspnea0
abnormal vision0
angina pectoris0
leg cramps0
gastritis0
arrhythmia0
chest pain0
cancer0
hepatic failure0
urinary urgency0
urinary retention0
pain0
decreased libido0
nausea0
syncope0
alopecia0
conjunctivitis0
bradycardia0
anorexia0
jaundice0
anemia0
pathological fracture0
back pain0
rectal hemorrhage0
fever0
hypercalcemia0
myocardial infarction0
dizziness0
confusion0
urinary tract infection0
urinary incontinence0
hypertension0
pruritus0
bone pain0
dry mouth0
skin carcinoma0
pleural effusion0
kidney calculus0
pharyngitis0
fatigue0
nocturia0
asthenia0
asthma0
diabetes mellitus0
bronchitis0
dysuria0
hypercholesterolemia0
herpes zoster0
coronary artery disease0
lung disorder0
hot flashes0
allergic reaction0
impotence0
hypoglycemia0
flushing0
tumor0
cerebrovascular accident0
pneumonia0
sinusitis0
breast tenderness0
chills0
cough0
flatulence0
skin ulcer0
alkaline phosphatase increased0
hyperglycemia0
edema0
atrial fibrillation0
weight loss0

Target

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Uniprot ID:CP2CJ_HUMAN
Synonyms:
(R)-limonene 6-monooxygenase
(S)-limonene 6-monooxygenase
(S)-limonene 7-monooxygenase
CYPIIC17
CYPIIC19
Cytochrome P450 2C19
Mephenytoin 4-hydroxylase
P450-11A
P450-254C
EC-Numbers:1.14.13.48
1.14.13.49
1.14.13.80
Organism:Homo sapiens
Human
PDB IDs:-

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: