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Drug-Target Interaction

Drug

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PubChem ID:23663992
Structure:
Synonyms:
(+)-Sodium
(+)-Sodium (3R,5S,6E)-7-(4-(p-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)-3-pyridyl)-3,5-dihydroxy-6-heptenoate
143201-11-0
6-Heptanoic acid, 7-(4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl)-3,5-dihydroxy-(S-(R*,S*-(E)))-, sodium salt
6-Heptenoic acid, 7-(4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(1-methylethyl)-3-pyridinyl)-3,5-dihydroxy-, monosodium salt, (3R,5S,6E)-
7-(4-(4-Fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)pyrid-3-yl)-3,5-dihydroxy-6-heptenoate sodium salt
Bay w 6228
Bay-w-6228
Baycol
Baycol (TN)
C26H33FNO5.Na
cerivastatin
CERIVASTATIN Na
CERIVASTATIN SODIUM
Cerivastatin sodium (JAN/USAN)
Cerivastatin sodium [USAN]
Certa
CHEBI:3559
CPD000469148
D00889
Lipobay
LS-74656
MLS001424071
Rivastatin
SAM001246554
SMR000469148
sodium [S-[R*,S*-(E)]]-7-[4-(4-fluorophenyl)-5-methoxymethyl)-2,6bis(1-methylethyl)-3-pyridinyl]-3,5-dihydroxy-6-heptenoate
ATC-Codes:

Target

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Uniprot ID:HMDH_HUMAN
Synonyms:
3-hydroxy-3-methylglutaryl-coenzyme A reductase
HMG-CoA reductase
EC-Numbers:1.1.1.34
Organism:Homo sapiens
Human
PDB IDs:1DQ8 1DQ9 1DQA 1HW8 1HW9 1HWI 1HWJ 1HWK 1HWL 2Q1L 2Q6B 2Q6C 2R4F 3BGL 3CCT 3CCW 3CCZ 3CD0 3CD5 3CD7 3CDA 3CDB
Structure:
3CDB

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: