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Drug-Target Interaction

Drug

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PubChem ID:231224
Structure:
Synonyms:
50-07-7
7-Amino-9.alpha.-methoxymitosane
Ametycin
Ametycine
Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a- methoxy-5-methyl-, carbamate (ester)
Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b- hexahydro-8a-methoxy-5-methyl-, [1aR-(1a.alpha.,8.beta.,8a.alpha.,8b.alpha.)]-
Mit-C
Mito-C
Mitocin-C
MITOMYCIN
Mitomycin C
Mitomycine
Mitomycinum
MMC
Mutamycin
Mytomycin
NCI-C04706
NCI60_002199
NSC26980
WLN: T D3 B556 BN EM JV MVTTT&J GO1 H1OVZ KZ L1
[(1ar,8r,8as,8br)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b
ATC-Codes:
Side-Effects:
Side-EffectFrequency
fibrosis0.0010
diarrhea0
burning sensation0
vomiting0
pulmonary edema0
pain0
hematemesis0
hypertension0
nausea0
thrombophlebitis0
anorexia0
alopecia0
dermatological problem0
syncope0
malaise0
somnolence0
leukopenia0
cancer0
asthenia0
ards0
erythema0
cellulitis0
fever0
blurred vision0
congestive heart failure0
cough0
thrombocytopenia0
confusion0
ulcer0
edema0
stomatitis0
hemolytic anemia0
renal failure0
dyspnea0
anemia0
fatigue0
headache0

Target

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Uniprot ID:NQO1_HUMAN
Synonyms:
Azoreductase
DT-diaphorase
DTD
Menadione reductase
NAD(P)H dehydrogenase [quinone] 1
NAD(P)H:quinone oxidoreductase 1
Phylloquinone reductase
QR1
Quinone reductase 1
EC-Numbers:1.6.5.2
Organism:Homo sapiens
Human
PDB IDs:1D4A 1DXO 1GG5 1H66 1H69 1KBO 1KBQ 1QBG 2F1O
Structure:
2F1O

Binding Affinities:

Ki: Kd:Ic 50:Ec50/Ic50:
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References: